FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1995456111> ?p ?o ?g. }

• W1995456111 endingPage "L507" @default.
• W1995456111 startingPage "L501" @default.
• W1995456111 abstract "Chloride transport is critical to many functions of the lung. Molecular defects in the best-known chloride channel, cystic fibrosis transmembrane conductance regulator (CFTR), lead to impaired function of airway defensins, hydration of airway surface fluid, and mucociliary clearance leading to chronic lung disease, and premature death, but do not cause defects in lung development. We examined the expression of one member of the ClC family of volume- and voltage-regulated channels using the ribonuclease protection assay and Western blot analysis in rats. ClC-5 mRNA and protein are most strongly expressed in the fetal lung, and expression is maintained although downregulated postnatally. In addition, using immunocytochemistry, we find that ClC-5 is predominantly expressed along the luminal surface of the airway epithelium, suggesting that ClC-5 may participate in lung chloride secretion. Identifying candidate genes for critical ion transport functions is essential for understanding normal lung morphogenesis and the pathophysiology of several lung diseases. In addition, the manipulation of non-CFTR chloride channels may provide a viable approach for treating cystic fibrosis lung disease." @default.
• W1995456111 created "2016-06-24" @default.
• W1995456111 creator A5001952415 @default.
• W1995456111 creator A5014418025 @default.
• W1995456111 creator A5029220053 @default.
• W1995456111 creator A5048425123 @default.
• W1995456111 creator A5073432707 @default.
• W1995456111 creator A5075518206 @default.
• W1995456111 date "2002-03-01" @default.
• W1995456111 modified "2023-09-23" @default.
• W1995456111 title "ClC-5: ontogeny of an alternative chloride channel in respiratory epithelia" @default.
• W1995456111 cites W1498851698 @default.
• W1995456111 cites W1588088482 @default.
• W1995456111 cites W1965068448 @default.
• W1995456111 cites W1980167030 @default.
• W1995456111 cites W1988101098 @default.
• W1995456111 cites W2003425871 @default.
• W1995456111 cites W2009638458 @default.
• W1995456111 cites W2013306854 @default.
• W1995456111 cites W2035150711 @default.
• W1995456111 cites W2047640546 @default.
• W1995456111 cites W2053191479 @default.
• W1995456111 cites W2053845290 @default.
• W1995456111 cites W2066872960 @default.
• W1995456111 cites W2071653080 @default.
• W1995456111 cites W2076831743 @default.
• W1995456111 cites W2085186575 @default.
• W1995456111 cites W2089592662 @default.
• W1995456111 cites W2096245959 @default.
• W1995456111 cites W2106761389 @default.
• W1995456111 cites W2111890068 @default.
• W1995456111 cites W2113074631 @default.
• W1995456111 cites W2117559755 @default.
• W1995456111 cites W2122484880 @default.
• W1995456111 cites W2122901539 @default.
• W1995456111 cites W2127392024 @default.
• W1995456111 cites W2159887906 @default.
• W1995456111 cites W2160815228 @default.
• W1995456111 cites W2167983900 @default.
• W1995456111 cites W2168400885 @default.
• W1995456111 cites W2199542526 @default.
• W1995456111 cites W2227786631 @default.
• W1995456111 cites W2279513316 @default.
• W1995456111 cites W2281025258 @default.
• W1995456111 cites W2336975164 @default.
• W1995456111 cites W2340220984 @default.
• W1995456111 cites W2407807942 @default.
• W1995456111 cites W2413997317 @default.
• W1995456111 cites W2415950711 @default.
• W1995456111 cites W2416620508 @default.
• W1995456111 cites W2418978538 @default.
• W1995456111 doi "https://doi.org/10.1152/ajplung.00207.2001" @default.
• W1995456111 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11839544" @default.
• W1995456111 hasPublicationYear "2002" @default.
• W1995456111 type Work @default.
• W1995456111 sameAs 1995456111 @default.
• W1995456111 citedByCount "15" @default.
• W1995456111 countsByYear W19954561112014 @default.
• W1995456111 countsByYear W19954561112015 @default.
• W1995456111 crossrefType "journal-article" @default.
• W1995456111 hasAuthorship W1995456111A5001952415 @default.
• W1995456111 hasAuthorship W1995456111A5014418025 @default.
• W1995456111 hasAuthorship W1995456111A5029220053 @default.
• W1995456111 hasAuthorship W1995456111A5048425123 @default.
• W1995456111 hasAuthorship W1995456111A5073432707 @default.
• W1995456111 hasAuthorship W1995456111A5075518206 @default.
• W1995456111 hasConcept C100094513 @default.
• W1995456111 hasConcept C104317684 @default.
• W1995456111 hasConcept C114682108 @default.
• W1995456111 hasConcept C126322002 @default.
• W1995456111 hasConcept C142724271 @default.
• W1995456111 hasConcept C145822097 @default.
• W1995456111 hasConcept C2776415932 @default.
• W1995456111 hasConcept C2776938444 @default.
• W1995456111 hasConcept C2777714996 @default.
• W1995456111 hasConcept C2778428886 @default.
• W1995456111 hasConcept C2910722709 @default.
• W1995456111 hasConcept C54355233 @default.
• W1995456111 hasConcept C55493867 @default.
• W1995456111 hasConcept C71924100 @default.
• W1995456111 hasConcept C86803240 @default.
• W1995456111 hasConcept C87568996 @default.
• W1995456111 hasConcept C95444343 @default.
• W1995456111 hasConceptScore W1995456111C100094513 @default.
• W1995456111 hasConceptScore W1995456111C104317684 @default.
• W1995456111 hasConceptScore W1995456111C114682108 @default.
• W1995456111 hasConceptScore W1995456111C126322002 @default.
• W1995456111 hasConceptScore W1995456111C142724271 @default.
• W1995456111 hasConceptScore W1995456111C145822097 @default.
• W1995456111 hasConceptScore W1995456111C2776415932 @default.
• W1995456111 hasConceptScore W1995456111C2776938444 @default.
• W1995456111 hasConceptScore W1995456111C2777714996 @default.
• W1995456111 hasConceptScore W1995456111C2778428886 @default.
• W1995456111 hasConceptScore W1995456111C2910722709 @default.
• W1995456111 hasConceptScore W1995456111C54355233 @default.
• W1995456111 hasConceptScore W1995456111C55493867 @default.
• W1995456111 hasConceptScore W1995456111C71924100 @default.
• W1995456111 hasConceptScore W1995456111C86803240 @default.

• next