Matches in SemOpenAlex for { <https://semopenalex.org/work/W1995497155> ?p ?o ?g. }
- W1995497155 endingPage "132" @default.
- W1995497155 startingPage "107" @default.
- W1995497155 abstract "Patients with solid and hematologic malignancies presenting with major bleeding or thrombotic complications, potentially life-ending events in a cancer patient's clinical course, usually require admission to an intensive care unit (ICU), making their diagnosis and management even more important for the intensivist. Given the significant advances in the diagnosis and treatment of almost all types of cancers in recent years, the intensivist is likely to encounter an ever-increasing number of cancer patients in the ICU setting with these complications. Abnormal hemostasis can occur as a consequence of both the pathology and treatment of cancer. Because cancer can have multiple effects on hemostatic equilibrium, treatment of these complications can be more complex than in the general population. This article reviews the physiology of coagulation and fibrinolysis, with special attention to those aspects that are most frequently altered in the setting of malignancy. The pathophysiology of bleeding and thrombotic complications specific to critically ill cancer patients are then detailed, and the diagnostic and therapeutic strategies are discussed. Special emphasis is placed on new cancer medications that have an effect on hemostasis, and on novel clotting and anticoagulant agents that are available to the intensivist for the management of these patients." @default.
- W1995497155 created "2016-06-24" @default.
- W1995497155 creator A5077326806 @default.
- W1995497155 creator A5078927879 @default.
- W1995497155 date "2010-01-01" @default.
- W1995497155 modified "2023-10-16" @default.
- W1995497155 title "Hematological Issues in Critically Ill Patients with Cancer" @default.
- W1995497155 cites W101114720 @default.
- W1995497155 cites W138570360 @default.
- W1995497155 cites W1511550220 @default.
- W1995497155 cites W1514768753 @default.
- W1995497155 cites W1565933916 @default.
- W1995497155 cites W177064649 @default.
- W1995497155 cites W1964306699 @default.
- W1995497155 cites W1970598617 @default.
- W1995497155 cites W1978771401 @default.
- W1995497155 cites W1979886901 @default.
- W1995497155 cites W1983198622 @default.
- W1995497155 cites W1983727955 @default.
- W1995497155 cites W1983760732 @default.
- W1995497155 cites W1984833612 @default.
- W1995497155 cites W1988310677 @default.
- W1995497155 cites W1990154448 @default.
- W1995497155 cites W1995884979 @default.
- W1995497155 cites W1999668293 @default.
- W1995497155 cites W2000639116 @default.
- W1995497155 cites W2000782581 @default.
- W1995497155 cites W2003376654 @default.
- W1995497155 cites W2004474968 @default.
- W1995497155 cites W2005434112 @default.
- W1995497155 cites W2006535208 @default.
- W1995497155 cites W2007086823 @default.
- W1995497155 cites W2007622568 @default.
- W1995497155 cites W2008627505 @default.
- W1995497155 cites W2009338993 @default.
- W1995497155 cites W2009578904 @default.
- W1995497155 cites W2012845039 @default.
- W1995497155 cites W2015962018 @default.
- W1995497155 cites W2016099099 @default.
- W1995497155 cites W2020513354 @default.
- W1995497155 cites W2021249043 @default.
- W1995497155 cites W2022713742 @default.
- W1995497155 cites W2022932023 @default.
- W1995497155 cites W2023001876 @default.
- W1995497155 cites W2027093124 @default.
- W1995497155 cites W2028757835 @default.
- W1995497155 cites W2030627370 @default.
- W1995497155 cites W2033408017 @default.
- W1995497155 cites W2034399120 @default.
- W1995497155 cites W2040731057 @default.
- W1995497155 cites W2041585489 @default.
- W1995497155 cites W2042775328 @default.
- W1995497155 cites W2044335440 @default.
- W1995497155 cites W2044889252 @default.
- W1995497155 cites W2045708268 @default.
- W1995497155 cites W2048602820 @default.
- W1995497155 cites W2051023095 @default.
- W1995497155 cites W2053022336 @default.
- W1995497155 cites W2064892114 @default.
- W1995497155 cites W2065058341 @default.
- W1995497155 cites W2065221552 @default.
- W1995497155 cites W2068476516 @default.
- W1995497155 cites W2069798103 @default.
- W1995497155 cites W2070063154 @default.
- W1995497155 cites W2071682406 @default.
- W1995497155 cites W2071998860 @default.
- W1995497155 cites W2072212668 @default.
- W1995497155 cites W2076173325 @default.
- W1995497155 cites W2076341305 @default.
- W1995497155 cites W2077585688 @default.
- W1995497155 cites W2080388518 @default.
- W1995497155 cites W2080571090 @default.
- W1995497155 cites W2081648065 @default.
- W1995497155 cites W2082036505 @default.
- W1995497155 cites W2088272024 @default.
- W1995497155 cites W2091509921 @default.
- W1995497155 cites W2095305778 @default.
- W1995497155 cites W2107624227 @default.
- W1995497155 cites W2112253049 @default.
- W1995497155 cites W2112564023 @default.
- W1995497155 cites W2113953182 @default.
- W1995497155 cites W2115019673 @default.
- W1995497155 cites W2115215139 @default.
- W1995497155 cites W2120630349 @default.
- W1995497155 cites W2122082665 @default.
- W1995497155 cites W2123622204 @default.
- W1995497155 cites W2128238959 @default.
- W1995497155 cites W2132918724 @default.
- W1995497155 cites W2140218159 @default.
- W1995497155 cites W2140699529 @default.
- W1995497155 cites W2144612836 @default.
- W1995497155 cites W2148532341 @default.
- W1995497155 cites W2149779707 @default.
- W1995497155 cites W2150121055 @default.
- W1995497155 cites W2150922204 @default.
- W1995497155 cites W2153503145 @default.
- W1995497155 cites W2154099252 @default.
- W1995497155 cites W2155484175 @default.