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- W1995529795 abstract "Understanding the frequency, risk factors, and management of anticoagulant-induced adverse events will assist clinicians in optimizing patient outcomes. The most frequent adverse event of all anticoagulants is major bleeding. Risk factors for major bleeding have been identified with the heparin compounds, the direct thrombin inhibitors (DTIs), fondaparinux, and warfarin therapy. Understanding these risk factors can help prevent bleeding events. For cases of clinically significant bleeding, reversal agents exist primarily for heparin and warfarin. Although less common, nonbleeding adverse events of anticoagulant therapy can also be life threatening. The heparin compounds are associated with the development of heparin-induced thrombocytopenia (HIT) and osteoporosis. HIT can result in life-threatening thrombosis and is usually managed with a DTI. Nonbleeding adverse events with warfarin therapy include skin reactions and the development of venous limb gangrene. Appropriate initiation of warfarin therapy may decrease the risk of venous limb gangrene." @default.
- W1995529795 created "2016-06-24" @default.
- W1995529795 creator A5025013886 @default.
- W1995529795 creator A5025254990 @default.
- W1995529795 creator A5083014625 @default.
- W1995529795 date "2004-10-01" @default.
- W1995529795 modified "2023-10-18" @default.
- W1995529795 title "Managing Complications of Anticoagulant Therapy" @default.
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