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- W1995540108 abstract "Significant progress has been made in the development of ribozymes for a wide variety of intracellular applications, including human gene therapy. Further advances are likely to come from innovative strategies to improve the delivery, expression, co-localization, targeting specificity and substrate turnover of ribozymes. In order to stimulate problem solving in these areas, this article discusses examples of recent successes in intracellular ribozyme applications, and identifies some of the obstacles that remain. In addition, some testable, but as yet untried, ideas for overcoming several of these obstacles are presented." @default.
- W1995540108 created "2016-06-24" @default.
- W1995540108 creator A5046038634 @default.
- W1995540108 date "1995-08-01" @default.
- W1995540108 modified "2023-09-23" @default.
- W1995540108 title "Controlled, targeted, intracellular expression of ribozymes: Progress and problems" @default.
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- W1995540108 doi "https://doi.org/10.1016/s0167-7799(00)88969-6" @default.
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