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• W1995541931 startingPage "173" @default.
• W1995541931 abstract "Permethrin resistance in the human head louse, Pediculus capitis De Geer (Anopulura: Pediculidae), has been reported worldwide, is associated with the knockdown phenotype, and elicits cross-resistance to DDT and the pyrethrins. Two point mutations, T929I and L932F, in the voltage-sensitive sodium channel α-subunit gene are responsible for permethrin resistance as a resistant haplotype (kdr-like). We have optimized a serial invasive signal amplification reaction (SISAR) protocol for the detection of these mutations using PCR amplified DNA fragments. SISAR distinguished all genotypes with high accuracy in a head louse population from Texas that was heterogeneous in terms of permethrin sensitivity. Using SISAR, resistance-conferring mutations are detected in a high throughput format, facilitating the efficient monitoring of permethrin resistance allele frequency in field populations." @default.
• W1995541931 created "2016-06-24" @default.
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• W1995541931 date "2004-11-01" @default.
• W1995541931 modified "2023-09-27" @default.
• W1995541931 title "Serial invasive signal amplification reaction for genotyping permethrin-resistant (kdr-like) human head lice, Pediculus capitis" @default.
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• W1995541931 doi "https://doi.org/10.1016/j.pestbp.2004.07.005" @default.
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