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- W1995555506 abstract "This paper describes the synthesis of a bicyclic β-amino acid scaffold in both pure enantiomeric forms and its application as chiral auxiliary in an intramolecular version of the Ugi multicomponent reaction (U-5C-4CR) to prepare α-amino acid derivatives of both d- and l-series in a straightforward and very stereoselective manner. The mild conditions required for the Ugi condensation and for the removal of the chiral auxiliary make this method very attractive to prepare a wide range of differently structured N-alkylated and unalkylated amino acid derivatives." @default.
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- W1995555506 date "2004-12-22" @default.
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- W1995555506 title "A Novel Highly Selective Chiral Auxiliary for the Asymmetric Synthesis of<scp>l</scp>- and<scp>d</scp>-α-Amino Acid Derivatives via a Multicomponent Ugi Reaction" @default.
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- W1995555506 doi "https://doi.org/10.1021/jo048389m" @default.
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