FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1995562783> ?p ?o ?g. }

• W1995562783 endingPage "258" @default.
• W1995562783 startingPage "249" @default.
• W1995562783 abstract "Palatable food disrupts normal appetite regulation, which may contribute to the etiology of obesity. Neuropeptide Y (NPY) and cholecystokinin play critical roles in the regulation of food intake and energy homeostasis, while adiponectin and carnitine palmitoyltransferase (CPT) are important for insulin sensitivity and fatty acid oxidation. This study examined the impact of short- and long-term consumption of palatable high-fat diet (HFD) on these critical metabolic regulators.Male C57BL/6 mice were exposed to laboratory chow (12% fat), or cafeteria-style palatable HFD (32% fat) for 2 or 10 weeks. Body weight and food intake were monitored throughout. Plasma leptin, hypothalamic NPY and cholecystokinin, and mRNA expression of leptin, adiponectin, their receptors and CPT-1, in fat and muscles were measured.Caloric intake of the palatable HFD group was 2-3 times greater than control, resulting in a 37% higher body weight. Fat mass was already increased at 2 weeks; plasma leptin concentrations were 2.4 and 9 times higher than control at 2 and 10 weeks, respectively. Plasma adiponectin was increased at 10 weeks. Muscle adiponectin receptor 1 was increased at 2 weeks, while CPT-1 mRNA was markedly upregulated by HFD at both time points. Hypothalamic NPY and cholecystokinin content were significantly decreased at 10 weeks.Palatable HFD induced hyperphagia, fat accumulation, increased adiponectin, leptin and muscle fatty acid oxidation, and reduced hypothalamic NPY and cholecystokinin. Our data suggest that the adaptive changes in hypothalamic NPY and muscle fatty acid oxidation are insufficient to reverse the progress of obesity and metabolic consequences induced by a palatable HFD." @default.
• W1995562783 created "2016-06-24" @default.
• W1995562783 creator A5011090841 @default.
• W1995562783 creator A5024814922 @default.
• W1995562783 creator A5033586136 @default.
• W1995562783 creator A5056263381 @default.
• W1995562783 creator A5082402585 @default.
• W1995562783 date "2007-09-04" @default.
• W1995562783 modified "2023-10-15" @default.
• W1995562783 title "Brain neuropeptide Y and CCK and peripheral adipokine receptors: temporal response in obesity induced by palatable diet" @default.
• W1995562783 cites W1561443084 @default.
• W1995562783 cites W1570490402 @default.
• W1995562783 cites W1580569338 @default.
• W1995562783 cites W1698695320 @default.
• W1995562783 cites W1790943011 @default.
• W1995562783 cites W1945866681 @default.
• W1995562783 cites W1964548443 @default.
• W1995562783 cites W1966103999 @default.
• W1995562783 cites W1969093549 @default.
• W1995562783 cites W1970163196 @default.
• W1995562783 cites W1971089461 @default.
• W1995562783 cites W1971452427 @default.
• W1995562783 cites W1971963895 @default.
• W1995562783 cites W1981511020 @default.
• W1995562783 cites W1987602959 @default.
• W1995562783 cites W1994378299 @default.
• W1995562783 cites W1996713062 @default.
• W1995562783 cites W1997978122 @default.
• W1995562783 cites W1998628654 @default.
• W1995562783 cites W2001937802 @default.
• W1995562783 cites W2005188818 @default.
• W1995562783 cites W2009189044 @default.
• W1995562783 cites W2011444761 @default.
• W1995562783 cites W2017244979 @default.
• W1995562783 cites W2020032681 @default.
• W1995562783 cites W2024474550 @default.
• W1995562783 cites W2030778616 @default.
• W1995562783 cites W2032777955 @default.
• W1995562783 cites W2041292777 @default.
• W1995562783 cites W2042706232 @default.
• W1995562783 cites W2043605177 @default.
• W1995562783 cites W2048098419 @default.
• W1995562783 cites W2059035261 @default.
• W1995562783 cites W2059683553 @default.
• W1995562783 cites W2063051075 @default.
• W1995562783 cites W2071928653 @default.
• W1995562783 cites W2075019242 @default.
• W1995562783 cites W2078076381 @default.
• W1995562783 cites W2090212753 @default.
• W1995562783 cites W2090931660 @default.
• W1995562783 cites W2092432949 @default.
• W1995562783 cites W2095556872 @default.
• W1995562783 cites W2102677290 @default.
• W1995562783 cites W2106693109 @default.
• W1995562783 cites W2108879058 @default.
• W1995562783 cites W2117012616 @default.
• W1995562783 cites W2118158977 @default.
• W1995562783 cites W2127862727 @default.
• W1995562783 cites W2130680018 @default.
• W1995562783 cites W2131278853 @default.
• W1995562783 cites W2143041174 @default.
• W1995562783 cites W2144450144 @default.
• W1995562783 cites W2144955458 @default.
• W1995562783 cites W2148391313 @default.
• W1995562783 cites W2154036516 @default.
• W1995562783 cites W2157933649 @default.
• W1995562783 cites W2160589226 @default.
• W1995562783 cites W2161715455 @default.
• W1995562783 cites W2168588760 @default.
• W1995562783 cites W2169370588 @default.
• W1995562783 cites W2170651583 @default.
• W1995562783 cites W2187535584 @default.
• W1995562783 cites W2187604823 @default.
• W1995562783 cites W4231924994 @default.
• W1995562783 doi "https://doi.org/10.1038/sj.ijo.0803716" @default.
• W1995562783 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17768423" @default.
• W1995562783 hasPublicationYear "2007" @default.
• W1995562783 type Work @default.
• W1995562783 sameAs 1995562783 @default.
• W1995562783 citedByCount "44" @default.
• W1995562783 countsByYear W19955627832012 @default.
• W1995562783 countsByYear W19955627832013 @default.
• W1995562783 countsByYear W19955627832014 @default.
• W1995562783 countsByYear W19955627832015 @default.
• W1995562783 countsByYear W19955627832016 @default.
• W1995562783 countsByYear W19955627832017 @default.
• W1995562783 countsByYear W19955627832018 @default.
• W1995562783 countsByYear W19955627832019 @default.
• W1995562783 countsByYear W19955627832020 @default.
• W1995562783 countsByYear W19955627832021 @default.
• W1995562783 countsByYear W19955627832022 @default.
• W1995562783 countsByYear W19955627832023 @default.
• W1995562783 crossrefType "journal-article" @default.
• W1995562783 hasAuthorship W1995562783A5011090841 @default.
• W1995562783 hasAuthorship W1995562783A5024814922 @default.
• W1995562783 hasAuthorship W1995562783A5033586136 @default.
• W1995562783 hasAuthorship W1995562783A5056263381 @default.
• W1995562783 hasAuthorship W1995562783A5082402585 @default.

• next