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• W1995586746 endingPage "460" @default.
• W1995586746 startingPage "453" @default.
• W1995586746 abstract "The past 15 years have seen a breakthrough in the field of innate immunity. In this Timeline article, the authors discuss the early events that led to the identification of Toll-like receptors as the prototype pattern-recognition receptors that link innate and adaptive immune responses. The discovery of Toll-like receptors (TLRs) was an important event for immunology research and was recognized as such with the awarding of the 2011 Nobel Prize in Physiology or Medicine to Jules Hoffmann and Bruce Beutler, who, together with Ralph Steinman, the third winner of the 2011 Nobel Prize and the person who discovered the dendritic cell, were pioneers in the field of innate immunity. TLRs have a central role in immunity — in this Timeline article, we describe the landmark findings that gave rise to this important field of research." @default.
• W1995586746 created "2016-06-24" @default.
• W1995586746 creator A5011747545 @default.
• W1995586746 creator A5066904739 @default.
• W1995586746 creator A5086513049 @default.
• W1995586746 date "2013-05-17" @default.
• W1995586746 modified "2023-10-11" @default.
• W1995586746 title "The history of Toll-like receptors — redefining innate immunity" @default.
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