FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1995602139> ?p ?o ?g. }

• W1995602139 endingPage "152" @default.
• W1995602139 startingPage "121" @default.
• W1995602139 abstract "This report reviews the efficacy of currently available antiarrhythmic agents for conversion of atrial fibrilation (AF) to normal sinus rhythm (NSR). A systematic search of literature in the English language was done on computerized databases, such as MEDLINE, EMBASE, and Current Contents, in reference lists, by manual searching, and in contact with expert informants. Published studies involving humans that described the use of antiarrhythmic therapy for conversion of AF to NSR were considered and only studies that examined the use of agents currently available in the United States were included. Studies exclusively describing antiarrhythmic therapy for conversion of postsurgical AF were excluded. The methodology and results of each trial were assessed and attempts were made to acquire additional information from investigators when needed. Assessment of methodological quality was incorporated into a levels-of-evidence scheme. Eighty-eight trials were included, of which 34 (39%) included a placebo group (level I data). We found in recent-onset AF of less than 7 days, intravenous (i.v.) procainamide, high-dose i.v. or high-dose combination i.v. and oral amiodarone, oral quinidine, oral flecainide, oral propafenone, and high-dose oral amiodarone are more effective than placebo for converting AF to NSR. In recent-onset AF of less than 90 days, i.v. ibutilide is more effective than placebo and i.v. procainamide. In chronic AF, oral dofetilide converts AF to NSR within 72 hours, and oral propafenone and amiodarone are effective after 30 days of therapy. We conclude than for conversion of recent-onset AF of less than 7 days, procainamide may be considered a preferred i.v. agent and propafenone a preferred oral agent. For conversion of recent-onset AF of longer duration (less than 90 days), i.v. ibutilide may be considered a preferred agent. For patients with chronic AF and left ventricular dysfunction, direct current cardioversion is the preferred conversion method. Larger, well-designed randomized controlled trials with clinically important endpoints in specific populations of AF patients are needed." @default.
• W1995602139 created "2016-06-24" @default.
• W1995602139 creator A5012193533 @default.
• W1995602139 creator A5037520504 @default.
• W1995602139 creator A5070741121 @default.
• W1995602139 date "2001-09-01" @default.
• W1995602139 modified "2023-10-03" @default.
• W1995602139 title "Pharmacologic conversion of atrial fibrillation: A systematic review of available evidence" @default.
• W1995602139 cites W1524089621 @default.
• W1995602139 cites W1531679198 @default.
• W1995602139 cites W1557874646 @default.
• W1995602139 cites W1952117966 @default.
• W1995602139 cites W1964087992 @default.
• W1995602139 cites W1964127609 @default.
• W1995602139 cites W1965755875 @default.
• W1995602139 cites W1966064887 @default.
• W1995602139 cites W1967121574 @default.
• W1995602139 cites W1971999136 @default.
• W1995602139 cites W1979081635 @default.
• W1995602139 cites W1979232262 @default.
• W1995602139 cites W1979503864 @default.
• W1995602139 cites W1987408696 @default.
• W1995602139 cites W1988911499 @default.
• W1995602139 cites W1989832493 @default.
• W1995602139 cites W1992816182 @default.
• W1995602139 cites W1992924686 @default.
• W1995602139 cites W1993401271 @default.
• W1995602139 cites W1996190255 @default.
• W1995602139 cites W1997611192 @default.
• W1995602139 cites W1998952740 @default.
• W1995602139 cites W1999199829 @default.
• W1995602139 cites W1999651496 @default.
• W1995602139 cites W2003719834 @default.
• W1995602139 cites W2008004260 @default.
• W1995602139 cites W2014041843 @default.
• W1995602139 cites W2014246616 @default.
• W1995602139 cites W2014707446 @default.
• W1995602139 cites W2016659665 @default.
• W1995602139 cites W2017179259 @default.
• W1995602139 cites W2017265343 @default.
• W1995602139 cites W2017833531 @default.
• W1995602139 cites W2019116262 @default.
• W1995602139 cites W2020509502 @default.
• W1995602139 cites W2020808414 @default.
• W1995602139 cites W2021320779 @default.
• W1995602139 cites W2023493040 @default.
• W1995602139 cites W2024783320 @default.
• W1995602139 cites W2025029346 @default.
• W1995602139 cites W2030929139 @default.
• W1995602139 cites W2032227708 @default.
• W1995602139 cites W2033630717 @default.
• W1995602139 cites W2033952448 @default.
• W1995602139 cites W2036605610 @default.
• W1995602139 cites W2036731296 @default.
• W1995602139 cites W2040420958 @default.
• W1995602139 cites W2041063379 @default.
• W1995602139 cites W2041491202 @default.
• W1995602139 cites W2044977706 @default.
• W1995602139 cites W2046513805 @default.
• W1995602139 cites W2047430853 @default.
• W1995602139 cites W2047496300 @default.
• W1995602139 cites W2048896225 @default.
• W1995602139 cites W2049375834 @default.
• W1995602139 cites W2049671328 @default.
• W1995602139 cites W2050391007 @default.
• W1995602139 cites W2052134184 @default.
• W1995602139 cites W2052230379 @default.
• W1995602139 cites W2054167248 @default.
• W1995602139 cites W2055836817 @default.
• W1995602139 cites W2058597157 @default.
• W1995602139 cites W2061927647 @default.
• W1995602139 cites W2064922645 @default.
• W1995602139 cites W2065010260 @default.
• W1995602139 cites W2066596473 @default.
• W1995602139 cites W2066805338 @default.
• W1995602139 cites W2067293168 @default.
• W1995602139 cites W2069249550 @default.
• W1995602139 cites W2069805683 @default.
• W1995602139 cites W2075177496 @default.
• W1995602139 cites W2076828944 @default.
• W1995602139 cites W2078357889 @default.
• W1995602139 cites W2079795099 @default.
• W1995602139 cites W2080973197 @default.
• W1995602139 cites W2083052773 @default.
• W1995602139 cites W2084631135 @default.
• W1995602139 cites W2084719078 @default.
• W1995602139 cites W2086499634 @default.
• W1995602139 cites W2086932585 @default.
• W1995602139 cites W2087213683 @default.
• W1995602139 cites W2087304492 @default.
• W1995602139 cites W2089571277 @default.
• W1995602139 cites W2089747678 @default.
• W1995602139 cites W2099144648 @default.
• W1995602139 cites W2101501238 @default.
• W1995602139 cites W2102450596 @default.
• W1995602139 cites W2107287569 @default.
• W1995602139 cites W2116170882 @default.
• W1995602139 cites W2122493711 @default.

• next