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- W1995632479 abstract "Biochemical changes in plasma nucleotides; ATP, ADP, AMP, and cAMP – that may be induced by Diabecity was investigated. The effect of oral antidiabetic drugs Glibenciamide (Daonil), Gliclazide (Diamicron); Triiodothyronine (T3) and combination of T3 with either of them was assessed in fasting condition and 2 hours postprandial. Diabetes per se induced non-significant changes in plasma levels of ATP, ADP and AMP, cAMP level was highly significantly lowered in diabeties than in normals. This change was accompanied by significant rise in ATP/cAMP ratio. The data presented show an impaired nucleotide changes in diabetes which can be corrected by treatment with oral antidiabetic drugs Daonil and Diamicron in the doses described and the levels of the different nucleotides were consequently reverted to normal, an effect induced by insulin release in response to drugs." @default.
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- W1995632479 date "1984-01-01" @default.
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- W1995632479 title "Effect of Oral Hypoglycemic Drugs, Triiodothyronine and Their Interaction on Nucleotide Metabolism in Maturity Onset Diabetics" @default.
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- W1995632479 doi "https://doi.org/10.1080/10256018408545021" @default.
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