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• W1995656393 abstract "Cell therapy for stroke may benefit from translational from Hess and Kondziolka and a biostatistics data coor-research guidelines to aid its entry into the clinic as a dination center by Lu. These investigators highlight thesafe and effective treatment. Failures of clinical trials rationale for establishing such consortium and its pur-using neuroprotective drugs in stroke patients, despite pose for evaluating the therapeutic potential of cell ther-promising laboratory findings, led to conference meet- apy for stroke in the present commentary (2). In view ofings under the banner of Stroke Therapy Academic In- cell therapy being marketed as “medical tourism” arounddustry Round table, or STAIR, whose main goal was the world, and the lifting of the US federal ban on em-to formulate recommendations designed to enhance the bryonic stem cell research, which is likely to gain fur-success of translating preclinical research on neuropro- ther public attention and scrutiny with respect to thetection into clinical application. In 2007, a group of sci- safety and efficacy of this treatment, this raises the ur-entists from academia and industry with interest in cell gency for an orderly transition of laboratory findingstherapy and stroke, together with representatives from into the clinic. The preclinical STEPS group serves notthe National Institute on Neurological Disorders and as an impediment to clinical trials of restorative treat-Stroke (NINDS) and the Food and Drug Administration, ment, but rather as a consultative faculty of scientistsconvened to outline STAIR-like criteria called Stem cell and clinicians who possess the desire of optimizing theTherapeutics as an Emerging Paradigm in Stroke, or therapeutic potential and assuring the safety of cell ther-STEPS, that will serve as a guide in the conduct of labo- apy for stroke. Whereas the current affiliations of thisratory research and clinical trials of restorative therapies, STEPS consortium are limited to the US, the near-termin particular cell therapy for stroke (3). The preclinical goal is to receive memberships from academic, industry,arm of STEPS specifically calls for the use of appro- and legislative organizations worldwide working on re-priate species for stroke modeling, the need for standard- storative therapy.ization of functional tests and outcomes, the requirementfor cell imaging and tracking, the incorporation of safety" @default.
• W1995656393 created "2016-06-24" @default.
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• W1995656393 date "2009-07-01" @default.
• W1995656393 modified "2023-10-16" @default.
• W1995656393 title "STEPS toward the Right Direction" @default.
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• W1995656393 doi "https://doi.org/10.3727/096368909x470892" @default.
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