Matches in SemOpenAlex for { <https://semopenalex.org/work/W1995698907> ?p ?o ?g. }
- W1995698907 endingPage "1688" @default.
- W1995698907 startingPage "1688" @default.
- W1995698907 abstract "We have observed that human CTL clones lose their specific cytolytic activity and cytokine production under certain stimulation conditions, while retaining an antigen-dependent growth pattern.These inactive CTL simultaneously lose their labeling by an HLA-peptide tetramer, even though the amount of TCR-CD3 at their surface is not reduced. The tetramer-negative cells recover tetramer staining and cytolytic activity after stimulation with tumor cells in the presence of a supernatant of activated lymphocytes. Our results suggest the existence of a new type of functional defect of CTL. They also indicate that tetramers may fail to reveal some CTL bearing the relevant TCR, even when such functionally arrested CTL retain the potential to participate in immune responses because their defect is reversible." @default.
- W1995698907 created "2016-06-24" @default.
- W1995698907 creator A5031213966 @default.
- W1995698907 creator A5036507285 @default.
- W1995698907 creator A5053168505 @default.
- W1995698907 creator A5072033611 @default.
- W1995698907 creator A5084242704 @default.
- W1995698907 creator A5089784419 @default.
- W1995698907 creator A5091738939 @default.
- W1995698907 date "2002-06-01" @default.
- W1995698907 modified "2023-10-17" @default.
- W1995698907 title "A reversible functional defect of CD8+ T lymphocytes involving loss of tetramer labeling" @default.
- W1995698907 cites W1521600055 @default.
- W1995698907 cites W1532252600 @default.
- W1995698907 cites W1533163141 @default.
- W1995698907 cites W1562441478 @default.
- W1995698907 cites W1599781349 @default.
- W1995698907 cites W1660737759 @default.
- W1995698907 cites W1829099663 @default.
- W1995698907 cites W1841969005 @default.
- W1995698907 cites W1969411212 @default.
- W1995698907 cites W1977273255 @default.
- W1995698907 cites W1979773132 @default.
- W1995698907 cites W1983558530 @default.
- W1995698907 cites W1985957558 @default.
- W1995698907 cites W1988530230 @default.
- W1995698907 cites W1998377021 @default.
- W1995698907 cites W2012120883 @default.
- W1995698907 cites W2023809975 @default.
- W1995698907 cites W2033360952 @default.
- W1995698907 cites W2040572245 @default.
- W1995698907 cites W2050253058 @default.
- W1995698907 cites W2053840907 @default.
- W1995698907 cites W2067069532 @default.
- W1995698907 cites W2068504553 @default.
- W1995698907 cites W2072122733 @default.
- W1995698907 cites W2076730875 @default.
- W1995698907 cites W2082990285 @default.
- W1995698907 cites W2094680268 @default.
- W1995698907 cites W2100427081 @default.
- W1995698907 cites W2102895333 @default.
- W1995698907 cites W2108336145 @default.
- W1995698907 cites W2115902968 @default.
- W1995698907 cites W2119232577 @default.
- W1995698907 cites W2121870374 @default.
- W1995698907 cites W2122411830 @default.
- W1995698907 cites W2125504851 @default.
- W1995698907 cites W2129971278 @default.
- W1995698907 cites W2130612676 @default.
- W1995698907 cites W2134438790 @default.
- W1995698907 cites W2136555855 @default.
- W1995698907 cites W2141782947 @default.
- W1995698907 cites W2145928191 @default.
- W1995698907 cites W2150492554 @default.
- W1995698907 cites W2159531745 @default.
- W1995698907 cites W2162864615 @default.
- W1995698907 cites W2171326835 @default.
- W1995698907 cites W27196345 @default.
- W1995698907 doi "https://doi.org/10.1002/1521-4141(200206)32:6<1688::aid-immu1688>3.0.co;2-9" @default.
- W1995698907 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12115652" @default.
- W1995698907 hasPublicationYear "2002" @default.
- W1995698907 type Work @default.
- W1995698907 sameAs 1995698907 @default.
- W1995698907 citedByCount "24" @default.
- W1995698907 countsByYear W19956989072012 @default.
- W1995698907 countsByYear W19956989072013 @default.
- W1995698907 countsByYear W19956989072014 @default.
- W1995698907 crossrefType "journal-article" @default.
- W1995698907 hasAuthorship W1995698907A5031213966 @default.
- W1995698907 hasAuthorship W1995698907A5036507285 @default.
- W1995698907 hasAuthorship W1995698907A5053168505 @default.
- W1995698907 hasAuthorship W1995698907A5072033611 @default.
- W1995698907 hasAuthorship W1995698907A5084242704 @default.
- W1995698907 hasAuthorship W1995698907A5089784419 @default.
- W1995698907 hasAuthorship W1995698907A5091738939 @default.
- W1995698907 hasBestOaLocation W19956989071 @default.
- W1995698907 hasConcept C114684123 @default.
- W1995698907 hasConcept C147483822 @default.
- W1995698907 hasConcept C147969180 @default.
- W1995698907 hasConcept C153911025 @default.
- W1995698907 hasConcept C154317977 @default.
- W1995698907 hasConcept C167672396 @default.
- W1995698907 hasConcept C181199279 @default.
- W1995698907 hasConcept C19317047 @default.
- W1995698907 hasConcept C202751555 @default.
- W1995698907 hasConcept C203014093 @default.
- W1995698907 hasConcept C2776090121 @default.
- W1995698907 hasConcept C2778886173 @default.
- W1995698907 hasConcept C2992881475 @default.
- W1995698907 hasConcept C49382859 @default.
- W1995698907 hasConcept C55493867 @default.
- W1995698907 hasConcept C73588182 @default.
- W1995698907 hasConcept C86803240 @default.
- W1995698907 hasConcept C8891405 @default.
- W1995698907 hasConcept C95444343 @default.
- W1995698907 hasConceptScore W1995698907C114684123 @default.
- W1995698907 hasConceptScore W1995698907C147483822 @default.
- W1995698907 hasConceptScore W1995698907C147969180 @default.