Matches in SemOpenAlex for { <https://semopenalex.org/work/W1995703612> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W1995703612 endingPage "428" @default.
- W1995703612 startingPage "411" @default.
- W1995703612 abstract "1. The influence of ouabain on net Ca movements was studied in human erythrocyte ghosts by atomic absorption spectrophotometry. 2. Ouabain (10(-5) M) showed a dual effect, altering both entry and exit of Ca from K-rich ghosts incubated in a high-Na medium in the presence of 10 mM-Ca. 3. Stimulation of Ca entry was observed in the first 15 min at 37 degrees C, whereas during the subsequent 15 min incubation ouabain elicited Ca extrusion. This latter effect was eliminated when the ouabain concentration was raised to 1 mM. 4. Ouabain-dependent Ca movements were abolished by replacing both internal K and external Na with choline. They were also absent from ghosts prepared at a high lytic ratio (1 : 100) or obtained from ATP-depleted cells. 5. A moderate increase in cell ATP enhanced the effect of ouabain on Ca efflux whilst it was eliminated at higher ATP levels. 6. The actions of ouabain markedly depended on the initial ADP/ATP ratio in ghosts, being optimal at about 2-5. 7. The results suggest that the effects of ouabain on Ca movements are mediated through the Na pump. Reversal of this pump in Na-rich K-free medium may provide the energy for active Ca transport." @default.
- W1995703612 created "2016-06-24" @default.
- W1995703612 creator A5004102058 @default.
- W1995703612 creator A5042020214 @default.
- W1995703612 date "1977-01-01" @default.
- W1995703612 modified "2023-09-26" @default.
- W1995703612 title "The alteration by ouabain of calcium movements in human red cell ghosts." @default.
- W1995703612 cites W1979845718 @default.
- W1995703612 cites W1983646788 @default.
- W1995703612 cites W1984386564 @default.
- W1995703612 cites W1986851259 @default.
- W1995703612 cites W1990421557 @default.
- W1995703612 cites W1994677150 @default.
- W1995703612 cites W2006238353 @default.
- W1995703612 cites W2011764922 @default.
- W1995703612 cites W2045647478 @default.
- W1995703612 cites W2064779468 @default.
- W1995703612 cites W2084588870 @default.
- W1995703612 cites W2084658283 @default.
- W1995703612 cites W2084707937 @default.
- W1995703612 cites W2085141045 @default.
- W1995703612 cites W2090129426 @default.
- W1995703612 cites W2095137948 @default.
- W1995703612 cites W2150530545 @default.
- W1995703612 cites W2166201936 @default.
- W1995703612 cites W2419274351 @default.
- W1995703612 cites W86020099 @default.
- W1995703612 doi "https://doi.org/10.1113/jphysiol.1977.sp011675" @default.
- W1995703612 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1307769" @default.
- W1995703612 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/839460" @default.
- W1995703612 hasPublicationYear "1977" @default.
- W1995703612 type Work @default.
- W1995703612 sameAs 1995703612 @default.
- W1995703612 citedByCount "7" @default.
- W1995703612 crossrefType "journal-article" @default.
- W1995703612 hasAuthorship W1995703612A5004102058 @default.
- W1995703612 hasAuthorship W1995703612A5042020214 @default.
- W1995703612 hasBestOaLocation W19957036122 @default.
- W1995703612 hasConcept C12554922 @default.
- W1995703612 hasConcept C126322002 @default.
- W1995703612 hasConcept C134018914 @default.
- W1995703612 hasConcept C178790620 @default.
- W1995703612 hasConcept C185592680 @default.
- W1995703612 hasConcept C24998067 @default.
- W1995703612 hasConcept C25642318 @default.
- W1995703612 hasConcept C2779133857 @default.
- W1995703612 hasConcept C519063684 @default.
- W1995703612 hasConcept C537181965 @default.
- W1995703612 hasConcept C55493867 @default.
- W1995703612 hasConcept C71924100 @default.
- W1995703612 hasConcept C86803240 @default.
- W1995703612 hasConceptScore W1995703612C12554922 @default.
- W1995703612 hasConceptScore W1995703612C126322002 @default.
- W1995703612 hasConceptScore W1995703612C134018914 @default.
- W1995703612 hasConceptScore W1995703612C178790620 @default.
- W1995703612 hasConceptScore W1995703612C185592680 @default.
- W1995703612 hasConceptScore W1995703612C24998067 @default.
- W1995703612 hasConceptScore W1995703612C25642318 @default.
- W1995703612 hasConceptScore W1995703612C2779133857 @default.
- W1995703612 hasConceptScore W1995703612C519063684 @default.
- W1995703612 hasConceptScore W1995703612C537181965 @default.
- W1995703612 hasConceptScore W1995703612C55493867 @default.
- W1995703612 hasConceptScore W1995703612C71924100 @default.
- W1995703612 hasConceptScore W1995703612C86803240 @default.
- W1995703612 hasIssue "2" @default.
- W1995703612 hasLocation W19957036121 @default.
- W1995703612 hasLocation W19957036122 @default.
- W1995703612 hasLocation W19957036123 @default.
- W1995703612 hasOpenAccess W1995703612 @default.
- W1995703612 hasPrimaryLocation W19957036121 @default.
- W1995703612 hasRelatedWork W1974105576 @default.
- W1995703612 hasRelatedWork W1984619393 @default.
- W1995703612 hasRelatedWork W2003842308 @default.
- W1995703612 hasRelatedWork W2025590009 @default.
- W1995703612 hasRelatedWork W2034768996 @default.
- W1995703612 hasRelatedWork W2054992011 @default.
- W1995703612 hasRelatedWork W2064236298 @default.
- W1995703612 hasRelatedWork W2064416809 @default.
- W1995703612 hasRelatedWork W2095093072 @default.
- W1995703612 hasRelatedWork W1996741910 @default.
- W1995703612 hasVolume "264" @default.
- W1995703612 isParatext "false" @default.
- W1995703612 isRetracted "false" @default.
- W1995703612 magId "1995703612" @default.
- W1995703612 workType "article" @default.