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- W1995715507 abstract "The hypoglycemic effect of the rhizomes of Polygonatum officinale (Liliaceae) was investigated in both normal and streptozotocin-induced diabetic mice. The methanol extract of rhizomes of Polygonatum officinale (PO) (800 mg/kg) reduced the blood glucose of normal mice from 170 +/- 3 to 136 +/- 5 mg/100 ml 4 hours after intraperitoneal administration (P < 0.001), and also significantly lowered the blood glucose of streptozotocin-induced diabetic mice from 696 +/- 60 to 407 +/- 35 mg/100 ml under similar conditions (P < 0.01). PO also suppressed epinephrine-induced hyperglycemia in mice. In addition, the n-butanol fraction of the methanol extract elicited a significant decrease in the blood glucose level of streptozotocin-induced diabetic mice after 4 hours (P < 0.05)." @default.
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- W1995715507 date "1994-06-01" @default.
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- W1995715507 title "Hypoglycemic Action of the Rhizomes of<i>Polygonatum officinale</i>in Normal and Diabetic Mice" @default.
- W1995715507 doi "https://doi.org/10.1055/s-2006-959458" @default.
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