Matches in SemOpenAlex for { <https://semopenalex.org/work/W1995731664> ?p ?o ?g. }
- W1995731664 abstract "The purpose of this study was to investigate possible mechanism of cocaine-induced hepatotoxicity and its potentiation by ethanol in mice. Ethanol (2 g/kg) and/or cocaine (25 mg/kg) injections were given as binge model (five injections in 3 days). Cocaine administration with or without ethanol caused an increase in lipid peroxidation in liver homogenate and its subcellular fractions. The greatest increases were observed in mitochondrial fraction following cocaine plus ethanol treatment. Also, glutathione (GSH) levels were increased in liver homogenate and its mitochondrial fractions after cocaine and cocaine plus ethanol treatment. Microsomal calcium sequestration was found to decrease in all treatments. These results suggest that increased lipid peroxidation and decreased microsomal calcium sequestration in the liver may play a possible role cocaine-induced hepatotoxicity and its potentiation by ethanol." @default.
- W1995731664 created "2016-06-24" @default.
- W1995731664 creator A5018006199 @default.
- W1995731664 creator A5031987195 @default.
- W1995731664 creator A5033115113 @default.
- W1995731664 creator A5036233898 @default.
- W1995731664 creator A5073579947 @default.
- W1995731664 creator A5079692247 @default.
- W1995731664 date "2000-02-01" @default.
- W1995731664 modified "2023-10-17" @default.
- W1995731664 title "The role of stimulated lipid peroxidation and impaired calcium sequestration in the enhancement of cocaine induced hepatotoxicity by ethanol" @default.
- W1995731664 cites W1775749144 @default.
- W1995731664 cites W1937563682 @default.
- W1995731664 cites W1978509529 @default.
- W1995731664 cites W1979617262 @default.
- W1995731664 cites W1983310681 @default.
- W1995731664 cites W1988644623 @default.
- W1995731664 cites W1996743535 @default.
- W1995731664 cites W2014443941 @default.
- W1995731664 cites W2019441049 @default.
- W1995731664 cites W2030206649 @default.
- W1995731664 cites W2033024401 @default.
- W1995731664 cites W2034154057 @default.
- W1995731664 cites W2034730687 @default.
- W1995731664 cites W2037713941 @default.
- W1995731664 cites W2046711849 @default.
- W1995731664 cites W2053692326 @default.
- W1995731664 cites W2063456128 @default.
- W1995731664 cites W2064660259 @default.
- W1995731664 cites W2065741201 @default.
- W1995731664 cites W2066507306 @default.
- W1995731664 cites W2073590726 @default.
- W1995731664 cites W2077374324 @default.
- W1995731664 cites W2093156528 @default.
- W1995731664 cites W2096948351 @default.
- W1995731664 cites W2123300577 @default.
- W1995731664 cites W2132324733 @default.
- W1995731664 cites W2155416693 @default.
- W1995731664 cites W2183125625 @default.
- W1995731664 cites W2023695237 @default.
- W1995731664 doi "https://doi.org/10.1016/s0376-8716(99)00061-7" @default.
- W1995731664 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10669057" @default.
- W1995731664 hasPublicationYear "2000" @default.
- W1995731664 type Work @default.
- W1995731664 sameAs 1995731664 @default.
- W1995731664 citedByCount "13" @default.
- W1995731664 countsByYear W19957316642015 @default.
- W1995731664 countsByYear W19957316642021 @default.
- W1995731664 crossrefType "journal-article" @default.
- W1995731664 hasAuthorship W1995731664A5018006199 @default.
- W1995731664 hasAuthorship W1995731664A5031987195 @default.
- W1995731664 hasAuthorship W1995731664A5033115113 @default.
- W1995731664 hasAuthorship W1995731664A5036233898 @default.
- W1995731664 hasAuthorship W1995731664A5073579947 @default.
- W1995731664 hasAuthorship W1995731664A5079692247 @default.
- W1995731664 hasConcept C170493617 @default.
- W1995731664 hasConcept C178790620 @default.
- W1995731664 hasConcept C181199279 @default.
- W1995731664 hasConcept C185592680 @default.
- W1995731664 hasConcept C25274449 @default.
- W1995731664 hasConcept C2776637226 @default.
- W1995731664 hasConcept C2778004101 @default.
- W1995731664 hasConcept C2780161600 @default.
- W1995731664 hasConcept C2780829032 @default.
- W1995731664 hasConcept C29730261 @default.
- W1995731664 hasConcept C519063684 @default.
- W1995731664 hasConcept C538909803 @default.
- W1995731664 hasConcept C55493867 @default.
- W1995731664 hasConcept C71924100 @default.
- W1995731664 hasConcept C87644729 @default.
- W1995731664 hasConcept C98274493 @default.
- W1995731664 hasConceptScore W1995731664C170493617 @default.
- W1995731664 hasConceptScore W1995731664C178790620 @default.
- W1995731664 hasConceptScore W1995731664C181199279 @default.
- W1995731664 hasConceptScore W1995731664C185592680 @default.
- W1995731664 hasConceptScore W1995731664C25274449 @default.
- W1995731664 hasConceptScore W1995731664C2776637226 @default.
- W1995731664 hasConceptScore W1995731664C2778004101 @default.
- W1995731664 hasConceptScore W1995731664C2780161600 @default.
- W1995731664 hasConceptScore W1995731664C2780829032 @default.
- W1995731664 hasConceptScore W1995731664C29730261 @default.
- W1995731664 hasConceptScore W1995731664C519063684 @default.
- W1995731664 hasConceptScore W1995731664C538909803 @default.
- W1995731664 hasConceptScore W1995731664C55493867 @default.
- W1995731664 hasConceptScore W1995731664C71924100 @default.
- W1995731664 hasConceptScore W1995731664C87644729 @default.
- W1995731664 hasConceptScore W1995731664C98274493 @default.
- W1995731664 hasLocation W19957316641 @default.
- W1995731664 hasLocation W19957316642 @default.
- W1995731664 hasOpenAccess W1995731664 @default.
- W1995731664 hasPrimaryLocation W19957316641 @default.
- W1995731664 hasRelatedWork W1973444905 @default.
- W1995731664 hasRelatedWork W1987458173 @default.
- W1995731664 hasRelatedWork W1996855040 @default.
- W1995731664 hasRelatedWork W2002811612 @default.
- W1995731664 hasRelatedWork W2005439229 @default.
- W1995731664 hasRelatedWork W2014565155 @default.
- W1995731664 hasRelatedWork W2025648961 @default.
- W1995731664 hasRelatedWork W2037713941 @default.
- W1995731664 hasRelatedWork W2040314731 @default.