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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1995751981> ?p ?o ?g. }

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• W1995751981 abstract "An efficient synthetic approach for the preparation of macrocyclic peptidomimetics for inhibition of HCV NS3 is presented. The macrocyclic core is built using ring-closing metathesis (RCM) of a tripeptidic diene. The presented approach allows the introduction of heteroatoms in strategic places along the macrocyclic ring. The methyl ester moiety in the RCM products was synthetically manipulated to install a keto-amide moiety via a Passerini reaction." @default.
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• W1995751981 date "2007-07-04" @default.
• W1995751981 modified "2023-10-09" @default.
• W1995751981 title "Application of Ring-Closing Metathesis for the Synthesis of Macrocyclic Peptidomimetics as Inhibitors of HCV NS3 Protease" @default.
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• W1995751981 doi "https://doi.org/10.1021/ol0711265" @default.
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