Matches in SemOpenAlex for { <https://semopenalex.org/work/W1995753312> ?p ?o ?g. }
- W1995753312 endingPage "304" @default.
- W1995753312 startingPage "294" @default.
- W1995753312 abstract "Anterior segment optical coherent tomography (AS-OCT) is used to further examine previous reports that ciliary muscle thickness (CMT) is increased in myopic eyes. With reference to temporal and nasal CMT, interrelationships between biometric and morphological characteristics of anterior and posterior segments are analysed for British-White and British-South-Asian adults with and without myopia.Data are presented for the right eyes of 62 subjects (British-White n = 39, British-South-Asian n = 23, aged 18-40 years) with a range of refractive error (mean spherical error (MSE (D)) -1.74 ± 3.26; range -10.06 to +4.38) and separated into myopes (MSE (D) <-0.50, range -10.06 to -0.56; n = 30) and non-myopes (MSE (D) ≥-0.50, -0.50 to +4.38; n = 32). Temporal and nasal ciliary muscle cross-sections were imaged using a Visante AS-OCT. Using Visante software, manual measures of nasal and temporal CMT (NCMT and TCMT respectively) were taken in successive posterior 1 mm steps from the scleral spur over a 3 mm distance (designated NCMT1, TCMT1 et seq). Measures of axial length and anterior chamber depth were taken with an IOLMaster biometer. MSE and corneal curvature (CC) measurements were taken with a Shin-Nippon auto-refractor. Magnetic resonance imaging was used to determine total ocular volume (OV) for 31 of the original subject group. Statistical comparisons and analyses were made using mixed repeated measures anovas, Pearson's correlation coefficient and stepwise forward multiple linear regression.MSE was significantly associated with CMT, with thicker CMT2 and CMT3 being found in the myopic eyes (p = 0.002). In non-myopic eyes TCMT1, TCMT2, NCMT1 and NCMT2 correlated significantly with MSE, AL and OV (p < 0.05). In contrast, myopic eyes failed generally to exhibit a significant correlation between CMT, MSE and axial length but notably retained a significant correlation between OV, TCMT2, TCMT3, NCMT2 and NCMT3 (p < 0.05). OV was found to be a significantly better predictor of TCMT2 and TCMT3 than AL by approximately a factor of two (p < 0.001). Anterior chamber depth was significantly associated with both temporal and nasal CMT2 and CMT3; TCMT1 correlated positively with CC. Ethnicity had no significant effect on differences in CMT.Increased CMT is associated with myopia. We speculate that the lack of correlation in myopic subjects between CMT and axial length, but not between CMT and OV, is evidence that disrupted feedback between the fovea and ciliary apparatus occurs in myopia development." @default.
- W1995753312 created "2016-06-24" @default.
- W1995753312 creator A5003889472 @default.
- W1995753312 creator A5025906766 @default.
- W1995753312 creator A5040077096 @default.
- W1995753312 creator A5056917202 @default.
- W1995753312 creator A5078287627 @default.
- W1995753312 date "2013-03-04" @default.
- W1995753312 modified "2023-10-16" @default.
- W1995753312 title "Ocular biometric correlates of ciliary muscle thickness in human myopia" @default.
- W1995753312 cites W103286883 @default.
- W1995753312 cites W109137918 @default.
- W1995753312 cites W1553268000 @default.
- W1995753312 cites W162809858 @default.
- W1995753312 cites W1964333524 @default.
- W1995753312 cites W1964651297 @default.
- W1995753312 cites W1966197741 @default.
- W1995753312 cites W1968847776 @default.
- W1995753312 cites W1973203863 @default.
- W1995753312 cites W1974004836 @default.
- W1995753312 cites W1976010113 @default.
- W1995753312 cites W1985872407 @default.
- W1995753312 cites W1990618872 @default.
- W1995753312 cites W1992743111 @default.
- W1995753312 cites W2005011661 @default.
- W1995753312 cites W2008215762 @default.
- W1995753312 cites W2011972434 @default.
- W1995753312 cites W2012738958 @default.
- W1995753312 cites W2014705594 @default.
- W1995753312 cites W2015795623 @default.
- W1995753312 cites W2019771766 @default.
- W1995753312 cites W2021446529 @default.
- W1995753312 cites W2031389243 @default.
- W1995753312 cites W2032267632 @default.
- W1995753312 cites W2036189684 @default.
- W1995753312 cites W2037232743 @default.
- W1995753312 cites W2042312938 @default.
- W1995753312 cites W2043270393 @default.
- W1995753312 cites W2044140253 @default.
- W1995753312 cites W2057808280 @default.
- W1995753312 cites W2060086170 @default.
- W1995753312 cites W2061010172 @default.
- W1995753312 cites W2067042743 @default.
- W1995753312 cites W2075218366 @default.
- W1995753312 cites W2079328748 @default.
- W1995753312 cites W2079709484 @default.
- W1995753312 cites W2084335054 @default.
- W1995753312 cites W2085061584 @default.
- W1995753312 cites W2091546620 @default.
- W1995753312 cites W2102919483 @default.
- W1995753312 cites W2112409498 @default.
- W1995753312 cites W2121311557 @default.
- W1995753312 cites W2129874519 @default.
- W1995753312 cites W2136686625 @default.
- W1995753312 cites W2150966546 @default.
- W1995753312 cites W2165887969 @default.
- W1995753312 cites W2440590776 @default.
- W1995753312 cites W4211118187 @default.
- W1995753312 cites W4254487968 @default.
- W1995753312 cites W1483695693 @default.
- W1995753312 doi "https://doi.org/10.1111/opo.12039" @default.
- W1995753312 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23452002" @default.
- W1995753312 hasPublicationYear "2013" @default.
- W1995753312 type Work @default.
- W1995753312 sameAs 1995753312 @default.
- W1995753312 citedByCount "40" @default.
- W1995753312 countsByYear W19957533122013 @default.
- W1995753312 countsByYear W19957533122014 @default.
- W1995753312 countsByYear W19957533122015 @default.
- W1995753312 countsByYear W19957533122016 @default.
- W1995753312 countsByYear W19957533122017 @default.
- W1995753312 countsByYear W19957533122018 @default.
- W1995753312 countsByYear W19957533122019 @default.
- W1995753312 countsByYear W19957533122020 @default.
- W1995753312 countsByYear W19957533122021 @default.
- W1995753312 countsByYear W19957533122022 @default.
- W1995753312 countsByYear W19957533122023 @default.
- W1995753312 crossrefType "journal-article" @default.
- W1995753312 hasAuthorship W1995753312A5003889472 @default.
- W1995753312 hasAuthorship W1995753312A5025906766 @default.
- W1995753312 hasAuthorship W1995753312A5040077096 @default.
- W1995753312 hasAuthorship W1995753312A5056917202 @default.
- W1995753312 hasAuthorship W1995753312A5078287627 @default.
- W1995753312 hasConcept C105702510 @default.
- W1995753312 hasConcept C105795698 @default.
- W1995753312 hasConcept C118487528 @default.
- W1995753312 hasConcept C119767625 @default.
- W1995753312 hasConcept C120665830 @default.
- W1995753312 hasConcept C121332964 @default.
- W1995753312 hasConcept C157660682 @default.
- W1995753312 hasConcept C2776148792 @default.
- W1995753312 hasConcept C2780718027 @default.
- W1995753312 hasConcept C2781135284 @default.
- W1995753312 hasConcept C33923547 @default.
- W1995753312 hasConcept C55078378 @default.
- W1995753312 hasConcept C71924100 @default.
- W1995753312 hasConceptScore W1995753312C105702510 @default.
- W1995753312 hasConceptScore W1995753312C105795698 @default.