Matches in SemOpenAlex for { <https://semopenalex.org/work/W1995774573> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W1995774573 endingPage "546" @default.
- W1995774573 startingPage "538" @default.
- W1995774573 abstract "beta-Mannosidosis, an inherited defect of glycoprotein catabolism previously identified in goats and humans, has been recently diagnosed in Salers cattle. This disorder is associated with deficiency of lysosomal beta-mannosidase and accumulation of oligosaccharides. Analysis of bovine beta-mannosidosis neuropathology was initiated to determine whether independently arising gene defects in cattle and goats result in expression of similar lesions. Brain, spinal cord, and selected peripheral nerves from seven affected newborn Salers calves and three normal newborn calves were available for gross, light microscopic, and electron microscopic analysis. Gross examination revealed hydrocephalus of variable severity and myelin deficiency in the cerebral hemispheres, cerebellum, and brainstem. Microscopic examination revealed cytoplasmic vacuolation, myelin deficiency, and axonal spheroids of similar type and distribution to that reported in affected goats. Cytoplasmic vacuolation resulting from lysosomal storage showed consistent variation among cell types. Myelin deficits were more severe in the cerebral hemispheres and cerebellum than in the spinal cord. Axonal spheroids occurred in the cerebrum, brainstem, cerebellum, and trigeminal nerve endings. The presence of similar lesions in bovine and caprine beta-mannosidosis supports a direct relationship with the gene defect." @default.
- W1995774573 created "2016-06-24" @default.
- W1995774573 creator A5004324645 @default.
- W1995774573 creator A5004438040 @default.
- W1995774573 creator A5065719609 @default.
- W1995774573 creator A5071308009 @default.
- W1995774573 date "1991-09-01" @default.
- W1995774573 modified "2023-10-13" @default.
- W1995774573 title "Neuropathology of Bovine β-Mannosidosis" @default.
- W1995774573 doi "https://doi.org/10.1097/00005072-199109000-00002" @default.
- W1995774573 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1895144" @default.
- W1995774573 hasPublicationYear "1991" @default.
- W1995774573 type Work @default.
- W1995774573 sameAs 1995774573 @default.
- W1995774573 citedByCount "28" @default.
- W1995774573 countsByYear W19957745732013 @default.
- W1995774573 countsByYear W19957745732014 @default.
- W1995774573 countsByYear W19957745732016 @default.
- W1995774573 countsByYear W19957745732018 @default.
- W1995774573 countsByYear W19957745732019 @default.
- W1995774573 countsByYear W19957745732020 @default.
- W1995774573 crossrefType "journal-article" @default.
- W1995774573 hasAuthorship W1995774573A5004324645 @default.
- W1995774573 hasAuthorship W1995774573A5004438040 @default.
- W1995774573 hasAuthorship W1995774573A5065719609 @default.
- W1995774573 hasAuthorship W1995774573A5071308009 @default.
- W1995774573 hasConcept C105702510 @default.
- W1995774573 hasConcept C134018914 @default.
- W1995774573 hasConcept C142724271 @default.
- W1995774573 hasConcept C169760540 @default.
- W1995774573 hasConcept C2778609137 @default.
- W1995774573 hasConcept C2779134260 @default.
- W1995774573 hasConcept C2779652256 @default.
- W1995774573 hasConcept C2780130745 @default.
- W1995774573 hasConcept C2780775167 @default.
- W1995774573 hasConcept C529278444 @default.
- W1995774573 hasConcept C533869091 @default.
- W1995774573 hasConcept C551621295 @default.
- W1995774573 hasConcept C71924100 @default.
- W1995774573 hasConcept C86803240 @default.
- W1995774573 hasConceptScore W1995774573C105702510 @default.
- W1995774573 hasConceptScore W1995774573C134018914 @default.
- W1995774573 hasConceptScore W1995774573C142724271 @default.
- W1995774573 hasConceptScore W1995774573C169760540 @default.
- W1995774573 hasConceptScore W1995774573C2778609137 @default.
- W1995774573 hasConceptScore W1995774573C2779134260 @default.
- W1995774573 hasConceptScore W1995774573C2779652256 @default.
- W1995774573 hasConceptScore W1995774573C2780130745 @default.
- W1995774573 hasConceptScore W1995774573C2780775167 @default.
- W1995774573 hasConceptScore W1995774573C529278444 @default.
- W1995774573 hasConceptScore W1995774573C533869091 @default.
- W1995774573 hasConceptScore W1995774573C551621295 @default.
- W1995774573 hasConceptScore W1995774573C71924100 @default.
- W1995774573 hasConceptScore W1995774573C86803240 @default.
- W1995774573 hasIssue "5" @default.
- W1995774573 hasLocation W19957745731 @default.
- W1995774573 hasLocation W19957745732 @default.
- W1995774573 hasOpenAccess W1995774573 @default.
- W1995774573 hasPrimaryLocation W19957745731 @default.
- W1995774573 hasRelatedWork W1971169887 @default.
- W1995774573 hasRelatedWork W1975501457 @default.
- W1995774573 hasRelatedWork W1978376937 @default.
- W1995774573 hasRelatedWork W2090387647 @default.
- W1995774573 hasRelatedWork W2124952435 @default.
- W1995774573 hasRelatedWork W2152104152 @default.
- W1995774573 hasRelatedWork W2156114205 @default.
- W1995774573 hasRelatedWork W2183852369 @default.
- W1995774573 hasRelatedWork W2811039846 @default.
- W1995774573 hasRelatedWork W4231064536 @default.
- W1995774573 hasVolume "50" @default.
- W1995774573 isParatext "false" @default.
- W1995774573 isRetracted "false" @default.
- W1995774573 magId "1995774573" @default.
- W1995774573 workType "article" @default.