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- W1995815904 abstract "Like most organisms, plants have endogenous biological clocks that coordinate internal events with the external environment. We used high-density oligonucleotide microarrays to examine gene expression in Arabidopsis and found that 6% of the more than 8000 genes on the array exhibited circadian changes in steady-state messenger RNA levels. Clusters of circadian-regulated genes were found in pathways involved in plant responses to light and other key metabolic pathways. Computational analysis of cycling genes allowed the identification of a highly conserved promoter motif that we found to be required for circadian control of gene expression. Our study presents a comprehensive view of the temporal compartmentalization of physiological pathways by the circadian clock in a eukaryote." @default.
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- W1995815904 date "2000-12-15" @default.
- W1995815904 modified "2023-10-17" @default.
- W1995815904 title "Orchestrated Transcription of Key Pathways in <i>Arabidopsis</i> by the Circadian Clock" @default.
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- W1995815904 doi "https://doi.org/10.1126/science.290.5499.2110" @default.
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