Matches in SemOpenAlex for { <https://semopenalex.org/work/W1995819021> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W1995819021 endingPage "238" @default.
- W1995819021 startingPage "235" @default.
- W1995819021 abstract "Effect of a cationic polymer, poly( l ‐lysine), on the kinetic properties of ionic channels formed by neutral gramicidin A (gA) and its negatively charged analogue O ‐pyromellitylgramicidin (OPg) in a bilayer lipid membrane is studied using a method of sensitized photoinactivation. This newly developed method is based on the analysis of transmembrane current transients induced by a flash in the presence of a photosensitizer. It has been shown previously that the time course of the flash‐induced current decrease in most cases follows a single exponential decay with an exponential factor (τ, the characteristic time of photoinactivation) that correlates well with the single‐channel lifetime. Addition of polylysine does not affect τ for gA channels, but causes a substantial increase in τ for OPg channels. This effect is reversed by addition of polyacrylic acid. The deceleration of the photoinactivation kinetics is ascribed to electrostatic interaction of polylysine with OPg probably resulting in OPg clustering. The latter can stabilize the channel state by reducing the rotational and lateral mobility of OPg monomers and dimers, and thus increase the single channel lifetime." @default.
- W1995819021 created "2016-06-24" @default.
- W1995819021 creator A5004813441 @default.
- W1995819021 creator A5006869709 @default.
- W1995819021 creator A5031442723 @default.
- W1995819021 creator A5037249560 @default.
- W1995819021 creator A5045616453 @default.
- W1995819021 date "1998-11-27" @default.
- W1995819021 modified "2023-09-23" @default.
- W1995819021 title "Polylysine decelerates kinetics of negatively charged gramicidin channels as shown by sensitized photoinactivation" @default.
- W1995819021 cites W1483662593 @default.
- W1995819021 cites W1964011658 @default.
- W1995819021 cites W1964442771 @default.
- W1995819021 cites W1981688870 @default.
- W1995819021 cites W1988259134 @default.
- W1995819021 cites W1991504644 @default.
- W1995819021 cites W1998167510 @default.
- W1995819021 cites W1999290641 @default.
- W1995819021 cites W2005963426 @default.
- W1995819021 cites W2014460597 @default.
- W1995819021 cites W2014535835 @default.
- W1995819021 cites W2023416593 @default.
- W1995819021 cites W2024179250 @default.
- W1995819021 cites W2029006988 @default.
- W1995819021 cites W2029997845 @default.
- W1995819021 cites W2053805880 @default.
- W1995819021 cites W2054764662 @default.
- W1995819021 cites W2056475985 @default.
- W1995819021 cites W2057262491 @default.
- W1995819021 cites W2059742976 @default.
- W1995819021 cites W2064451603 @default.
- W1995819021 cites W2071749640 @default.
- W1995819021 cites W2073699216 @default.
- W1995819021 cites W2073737852 @default.
- W1995819021 cites W2079069988 @default.
- W1995819021 cites W2085468084 @default.
- W1995819021 cites W2088586393 @default.
- W1995819021 cites W2088895209 @default.
- W1995819021 cites W2151216215 @default.
- W1995819021 cites W60447612 @default.
- W1995819021 cites W94441908 @default.
- W1995819021 doi "https://doi.org/10.1016/s0014-5793(98)01462-8" @default.
- W1995819021 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9862462" @default.
- W1995819021 hasPublicationYear "1998" @default.
- W1995819021 type Work @default.
- W1995819021 sameAs 1995819021 @default.
- W1995819021 citedByCount "14" @default.
- W1995819021 countsByYear W19958190212012 @default.
- W1995819021 countsByYear W19958190212017 @default.
- W1995819021 countsByYear W19958190212021 @default.
- W1995819021 crossrefType "journal-article" @default.
- W1995819021 hasAuthorship W1995819021A5004813441 @default.
- W1995819021 hasAuthorship W1995819021A5006869709 @default.
- W1995819021 hasAuthorship W1995819021A5031442723 @default.
- W1995819021 hasAuthorship W1995819021A5037249560 @default.
- W1995819021 hasAuthorship W1995819021A5045616453 @default.
- W1995819021 hasConcept C121332964 @default.
- W1995819021 hasConcept C12554922 @default.
- W1995819021 hasConcept C148898269 @default.
- W1995819021 hasConcept C185592680 @default.
- W1995819021 hasConcept C2779650302 @default.
- W1995819021 hasConcept C2780075363 @default.
- W1995819021 hasConcept C39944091 @default.
- W1995819021 hasConcept C41625074 @default.
- W1995819021 hasConcept C55493867 @default.
- W1995819021 hasConcept C62520636 @default.
- W1995819021 hasConcept C86803240 @default.
- W1995819021 hasConceptScore W1995819021C121332964 @default.
- W1995819021 hasConceptScore W1995819021C12554922 @default.
- W1995819021 hasConceptScore W1995819021C148898269 @default.
- W1995819021 hasConceptScore W1995819021C185592680 @default.
- W1995819021 hasConceptScore W1995819021C2779650302 @default.
- W1995819021 hasConceptScore W1995819021C2780075363 @default.
- W1995819021 hasConceptScore W1995819021C39944091 @default.
- W1995819021 hasConceptScore W1995819021C41625074 @default.
- W1995819021 hasConceptScore W1995819021C55493867 @default.
- W1995819021 hasConceptScore W1995819021C62520636 @default.
- W1995819021 hasConceptScore W1995819021C86803240 @default.
- W1995819021 hasIssue "1-2" @default.
- W1995819021 hasLocation W19958190211 @default.
- W1995819021 hasLocation W19958190212 @default.
- W1995819021 hasOpenAccess W1995819021 @default.
- W1995819021 hasPrimaryLocation W19958190211 @default.
- W1995819021 hasRelatedWork W2020705112 @default.
- W1995819021 hasRelatedWork W2024914238 @default.
- W1995819021 hasRelatedWork W2094539492 @default.
- W1995819021 hasRelatedWork W2419492187 @default.
- W1995819021 hasRelatedWork W2580174306 @default.
- W1995819021 hasRelatedWork W262155870 @default.
- W1995819021 hasRelatedWork W3110055093 @default.
- W1995819021 hasRelatedWork W3171224921 @default.
- W1995819021 hasRelatedWork W4200234135 @default.
- W1995819021 hasRelatedWork W4386256037 @default.
- W1995819021 hasVolume "440" @default.
- W1995819021 isParatext "false" @default.
- W1995819021 isRetracted "false" @default.
- W1995819021 magId "1995819021" @default.
- W1995819021 workType "article" @default.