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- W1995833243 abstract "Abstract Protein–protein interactions represent a highly populated class of targets for drug discovery. However, such systems present a number of unique challenges. This review presents an analysis of individual protein‐protein interaction systems which have recently yielded success in discovering drug‐like inhibitors. The structural characteristics of the protein binding sites and the attributes of the small molecule ligands are focused upon, in an attempt to derive commonly shared principles that may be of general usefulness in future drug discovery efforts within this target class. © 2006 Wiley Periodicals, Inc. Biopolymers (Pept Sci) 84: 535–552, 2006 This article was originally published online as an accepted preprint. The “Published Online” date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at biopolymers@wiley.com" @default.
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- W1995833243 date "2006-01-01" @default.
- W1995833243 modified "2023-10-17" @default.
- W1995833243 title "Protein–protein interactions as targets for small molecule drug discovery" @default.
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- W1995833243 doi "https://doi.org/10.1002/bip.20608" @default.
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