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- W1995841308 abstract "Background: Severe generalized spastic movement disorders of various aetiologies often involve the jaw muscles and lead to a spastic trismus with masseter muscle hypertonia. We report a placebo‐controlled randomized study on patients with spastic trismus. Methods: Eleven patients with masseter hypertonia because of stroke, hypoxic encephalopathy or traumatic brain injury were allocated to either botulinum toxin serotype B (BoNT/B) injections into the masseter muscles or placebo treatment. The dental gap, the amount of saliva, salivation scales, and a clinical goal attainment were evaluated. Results: Three weeks after injection the BoNT/B group showed a significantly increased mouth opening compared with placebo treatment ( P < 0.05). In addition to the muscle paralysing effect, a goal attainment scale demonstrated a clinical benefit for the BoNT/B group ( P < 0.01). Conclusions: Botulinum toxin serotype B injections into the masseter muscles effectively reduce hypertonia and provide for better mouth opening, thereby contributing to a positive and desired clinical goal." @default.
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- W1995841308 date "2009-11-17" @default.
- W1995841308 modified "2023-10-12" @default.
- W1995841308 title "Botulinum toxin B increases mouth opening in patients with spastic trismus" @default.
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- W1995841308 doi "https://doi.org/10.1111/j.1468-1331.2009.02723.x" @default.
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