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- W1995857710 abstract "Matrix metalloproteinases (MMPs) and their endogenous inhibitors, tissue inhibitors of MMPs (TIMPs), are produced in the gastrointestinal tract by several structural cells. The balance between MMPs and TIMPs is essential for many physiological processes in the gut. However, imbalance between MMPs and TIMPs plays an important role in the pathophysiology of diverse intestinal inflammatory conditions. We reviewed the role of the MMP/TIMP system in the pathogenesis of intestinal inflammatory diseases and pharmacologic perspectives for the use of compounds that restore the MMP/TIMP balance." @default.
- W1995857710 created "2016-06-24" @default.
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- W1995857710 date "2006-04-27" @default.
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- W1995857710 title "Role of Matrix Metalloproteinases in Intestinal Inflammation" @default.
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- W1995857710 doi "https://doi.org/10.1124/jpet.106.103465" @default.
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