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- W1995957100 abstract "Anthonisen NR, Skeans MA, Wise RA, et al . The effects of a smoking cessation intervention on 14.5-year mortality: a randomized clinical trial. Ann Intern Med 2005;142:233–9. [OpenUrl][1][CrossRef][2][PubMed][3][Web of Science][4] Q In current smokers with asymptomatic airway obstruction, is a smoking cessation programme (SCP) with or without inhaled ipratropium more effective than usual care (UC) for reducing all cause mortality? Clinical impact ratings GP/FP/Primary care ★★★★★☆☆ IM/Ambulatory care ★★★★★★☆ Respirology ★★★★★★☆ ### ![Graphic][5]</img>Design: randomised placebo controlled trial (Lung Health Study [LHS]). ### ![Graphic][6]</img>Allocation: unclear allocation concealment.* ### ![Graphic][7]</img>Blinding: unblinded.* ### ![Graphic][8]</img>Follow up period: 14.5 years. ### ![Graphic][9]</img>Setting: 10 clinical centres in the US and Canada. ### ![Graphic][10]</img>Participants: 5887 smokers 35–60 years of age (mean age 48 y, 63% men) who had asymptomatic airway obstruction. ### ![Graphic][11]</img>Intervention: a 10 week SCP that included a strong physician message and 12 two hour group sessions using behaviour modification and nicotine gum, plus either inhaled ipratropium (n = 1961) or a placebo inhaler (n = 1962). … [1]: {openurl}?query=rft.jtitle%253DAnnals%2Bof%2BInternal%2BMedicine%26rft.stitle%253DANN%2BINTERN%2BMED%26rft.issn%253D0003-4819%26rft.aulast%253DAnthonisen%26rft.auinit1%253DN.%2BR.%26rft.volume%253D142%26rft.issue%253D4%26rft.spage%253D233%26rft.epage%253D239%26rft.atitle%253DThe%2BEffects%2Bof%2Ba%2BSmoking%2BCessation%2BIntervention%2Bon%2B14.5-Year%2BMortality%253A%2BA%2BRandomized%2BClinical%2BTrial%26rft_id%253Dinfo%253Adoi%252F10.7326%252F0003-4819-142-4-200502150-00005%26rft_id%253Dinfo%253Apmid%252F15710956%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=10.7326/0003-4819-142-4-200502150-00005&link_type=DOI [3]: /lookup/external-ref?access_num=15710956&link_type=MED&atom=%2Febmed%2F10%2F5%2F143.atom [4]: /lookup/external-ref?access_num=000227239500001&link_type=ISI [5]: /embed/inline-graphic-1.gif [6]: /embed/inline-graphic-2.gif [7]: /embed/inline-graphic-3.gif [8]: /embed/inline-graphic-4.gif [9]: /embed/inline-graphic-5.gif [10]: /embed/inline-graphic-6.gif [11]: /embed/inline-graphic-7.gif" @default.
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- W1995957100 date "2005-10-01" @default.
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- W1995957100 title "A smoking cessation programme plus inhaled ipratropium improved survival in asymptomatic airway obstruction" @default.
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!["Anthonisen NR, Skeans MA, Wise RA, et al . The effects of a smoking cessation intervention on 14.5-year mortality: a randomized clinical trial. Ann Intern Med 2005;142:233–9. [OpenUrl][1][CrossRef][2][PubMed][3][Web of Science][4] Q In current smokers with asymptomatic airway obstruction, is a smoking cessation programme (SCP) with or without inhaled ipratropium more effective than usual care (UC) for reducing all cause mortality? Clinical impact ratings GP/FP/Primary care ★★★★★☆☆ IM/Ambulatory care ★★★★★★☆ Respirology ★★★★★★☆ ### ![Graphic][5]</img>Design: randomised placebo controlled trial (Lung Health Study [LHS]). ### ![Graphic][6]</img>Allocation: unclear allocation concealment.* ### ![Graphic][7]</img>Blinding: unblinded.* ### ![Graphic][8]</img>Follow up period: 14.5 years. ### ![Graphic][9]</img>Setting: 10 clinical centres in the US and Canada. ### ![Graphic][10]</img>Participants: 5887 smokers 35–60 years of age (mean age 48 y, 63% men) who had asymptomatic airway obstruction. ### ![Graphic][11]</img>Intervention: a 10 week SCP that included a strong physician message and 12 two hour group sessions using behaviour modification and nicotine gum, plus either inhaled ipratropium (n = 1961) or a placebo inhaler (n = 1962). … [1]: 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