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- W1995965400 abstract "Modern studies of sound-induced tympanic membrane (TM) motion include digital holography and optical-coherence tomography. These techniques generate high-definition maps of the motion of human and animal TMs that define and quantify spatial patterns of motion. In order to compare such patterns quantitatively between multiple specimens, a common coordinate system is necessary. Differences in the relative position of the sensor and the measured sample induce differences in magnification, shape, and location of the resulting TM image. A registration algorithm was implemented as follows: (1) The plot of the phase of motion at low frequencies was filtered with a moving 2D variance filter to differentiate the membrane from the bone in both reference and moving images (a process called segmentation). (2) A routine calculated the covariance matrix of the segmented images to measure its second central moment. (3) The images were aligned and warped on the basis of their centroid and moment. The method is about ten times faster than state-of-the-art intensity based registration, and the average squared errors of the pixel intensities after registration are not statistically different. The method is an efficient strategy to align TM surface images." @default.
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- W1995965400 date "2014-04-01" @default.
- W1995965400 modified "2023-10-17" @default.
- W1995965400 title "Aligning digital holography images of tympanic membrane motion" @default.
- W1995965400 doi "https://doi.org/10.1121/1.4878020" @default.
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