Matches in SemOpenAlex for { <https://semopenalex.org/work/W1995996970> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W1995996970 abstract "To investigate the auditory impairment induced by the administration of aminoglycosides in the newborn, the shuttle box method was employed to measure the auditory threshold of rats. Five groups of newborn rats were administered kanamycin sulfate, 250 and 500 mg/kg, streptomycin sulfate, 250 and 500 mg/kg, or 1 ml/kg saline, subcutaneously, from the 10th to the 15th day of birth. The auditory threshold of the control group could be measured by the shuttle box method at the age of 100 days. The auditory threshold of the control group was 52.1 +/- 1.0 dB (N = 14). The auditory thresholds of the animals treated with kanamycin 250 mg/kg and streptomycin 250 mg/kg groups were measured in only 1 (61.0 dB) and 4 (64.8 +/- 4.6 dB), respectively, since the auditory toxicity of these drugs in newborn rats was stronger than adult rats. Auditory threshold of the 250 mg/kg streptomycin group was significantly higher than that of the control group. The animals which could not be measured for the auditory threshold had the ability to acquire conditioned avoidance response when both conditioned stimuli (tone and light) were presented. However, after differentiation of the stimuli, the percent avoidance to tone in these animals was significantly decreased and did not recover by the following trainings, while the percent avoidance to light was similar to that before the differentiation.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
- W1995996970 created "2016-06-24" @default.
- W1995996970 creator A5055747865 @default.
- W1995996970 creator A5059065588 @default.
- W1995996970 creator A5089387849 @default.
- W1995996970 date "1985-01-01" @default.
- W1995996970 modified "2023-09-24" @default.
- W1995996970 title "Measurement of an auditory impairment induced by aminoglycosides using a shuttle box method in newborn rats." @default.
- W1995996970 doi "https://doi.org/10.1254/fpj.86.377" @default.
- W1995996970 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4093075" @default.
- W1995996970 hasPublicationYear "1985" @default.
- W1995996970 type Work @default.
- W1995996970 sameAs 1995996970 @default.
- W1995996970 citedByCount "1" @default.
- W1995996970 crossrefType "journal-article" @default.
- W1995996970 hasAuthorship W1995996970A5055747865 @default.
- W1995996970 hasAuthorship W1995996970A5059065588 @default.
- W1995996970 hasAuthorship W1995996970A5089387849 @default.
- W1995996970 hasBestOaLocation W19959969701 @default.
- W1995996970 hasConcept C104317684 @default.
- W1995996970 hasConcept C126322002 @default.
- W1995996970 hasConcept C185592680 @default.
- W1995996970 hasConcept C2775843808 @default.
- W1995996970 hasConcept C2777443451 @default.
- W1995996970 hasConcept C2779841869 @default.
- W1995996970 hasConcept C2780920689 @default.
- W1995996970 hasConcept C29730261 @default.
- W1995996970 hasConcept C42219234 @default.
- W1995996970 hasConcept C501593827 @default.
- W1995996970 hasConcept C548259974 @default.
- W1995996970 hasConcept C55493867 @default.
- W1995996970 hasConcept C71924100 @default.
- W1995996970 hasConceptScore W1995996970C104317684 @default.
- W1995996970 hasConceptScore W1995996970C126322002 @default.
- W1995996970 hasConceptScore W1995996970C185592680 @default.
- W1995996970 hasConceptScore W1995996970C2775843808 @default.
- W1995996970 hasConceptScore W1995996970C2777443451 @default.
- W1995996970 hasConceptScore W1995996970C2779841869 @default.
- W1995996970 hasConceptScore W1995996970C2780920689 @default.
- W1995996970 hasConceptScore W1995996970C29730261 @default.
- W1995996970 hasConceptScore W1995996970C42219234 @default.
- W1995996970 hasConceptScore W1995996970C501593827 @default.
- W1995996970 hasConceptScore W1995996970C548259974 @default.
- W1995996970 hasConceptScore W1995996970C55493867 @default.
- W1995996970 hasConceptScore W1995996970C71924100 @default.
- W1995996970 hasLocation W19959969701 @default.
- W1995996970 hasLocation W19959969702 @default.
- W1995996970 hasOpenAccess W1995996970 @default.
- W1995996970 hasPrimaryLocation W19959969701 @default.
- W1995996970 hasRelatedWork W126055891 @default.
- W1995996970 hasRelatedWork W1992200977 @default.
- W1995996970 hasRelatedWork W1999285254 @default.
- W1995996970 hasRelatedWork W2025191506 @default.
- W1995996970 hasRelatedWork W2049921722 @default.
- W1995996970 hasRelatedWork W2054187553 @default.
- W1995996970 hasRelatedWork W2109268821 @default.
- W1995996970 hasRelatedWork W2203289615 @default.
- W1995996970 hasRelatedWork W2404749731 @default.
- W1995996970 hasRelatedWork W150177162 @default.
- W1995996970 isParatext "false" @default.
- W1995996970 isRetracted "false" @default.
- W1995996970 magId "1995996970" @default.
- W1995996970 workType "article" @default.