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• W1996001555 abstract "Abstract Both sexual cycle and sleep circadian rhythms are disturbed by aging. It is known that these aging changes are involved in the functional disorder of the central nervous system. An attempt to clarify the central mechanism of the aging process in rats was made by comparing age‐related changes in the sleep circadian rhythm and sexual cycle with those in several centrally manipulated aging models. Old persistent estrous (PE with circadian PS: 9–14 months old) and 6‐OHDA treated rats known to show postsynaptic supersensitivity of s ‐adrenergic receptor showed the enhanced circadian rhythmicity in both slow wave (SWS) and paradoxical (PS) sleep, but PE with ultradian PS (11–24 months old) and intra‐suprachiasmatic (SCN) PCPA injected rats showed the circadian SWS and the ultradian PS rhythm. Old pseudopregnant (PSP) rats and rats bearing medial preoptic lesion indicated the circadian SWS and the semicircadian PS rhythm with higher night PS amounts. Old persistent diestrous (PD) and the rat bearing lar..." @default.
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• W1996001555 date "1988-12-01" @default.
• W1996001555 modified "2023-09-24" @default.
• W1996001555 title "Changes in circadian sleep rhythm in aged female rats and their neural mechanisms involved" @default.
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• W1996001555 doi "https://doi.org/10.1080/09291018809359983" @default.
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