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- W1996032821 abstract "In Brief Introduction: Research indicates that spectrophotometric intracutaneous analysis (SIAscopy) may be a useful adjunct in nonmelanoma skin cancer (NMSC) diagnosis. A study was performed to prospectively assess the accuracy of NMSC diagnosis by the SIAscope as compared with a clinician. Methods: Prior to excision, 323 consecutive lesions were examined and diagnosed by a clinician. SIAgraphs were then taken of the lesions and examined blindly at a later date. Diagnostic accuracy for the clinician and SIAscope was compared between the clinician and SIAscope and to histology. Results: Sensitivity, specificity, positive and negative predictive values for clinical diagnoses were 95.6%, 75.8%, 0.79, and 0.95, respectively. Results for SIA diagnoses were 97.5%, 86.7%, 0.88, and 0.97. Statistical comparison revealed comparable sensitivities for the 2 groups but significantly better specificity for the SIAscope at the 95% confidence level. Conclusion: This study indicates that the SIAscope may be useful in NMSC diagnosis, with accuracies comparable to a clinician. Three hundred twenty-three Spectrophotometric Intracutaneous Analyzer studies were performed on suspected nonmelanoma skin cancers. Clinical diagnostic sensitivity was 95.6%, specificity was 75.8%, positive predictive value was 0.79, and negative predictive value was 0.95." @default.
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- W1996032821 date "2007-02-01" @default.
- W1996032821 modified "2023-09-25" @default.
- W1996032821 title "A Prospective Comparison of Spectrophotometric Intracutaneous Analysis to Clinical Judgment in the Diagnosis of Nonmelanoma Skin Cancer" @default.
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- W1996032821 doi "https://doi.org/10.1097/01.sap.0000235476.10517.bb" @default.
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