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- W1996046925 abstract "The concentration of LH and pro-gesterone in jugular venous plasma and the secre-tion of steroids by the ovary were measured every 10 minutes for 2 hours on days 12, 14, and 16 ofthe estrous cycle in 5 ewes with utero-ovarian auto-transplants. A pulse of LH occurred about onceevery 2 hours, when the concentration rose froma basal level of 0.5J7 ± 0.08 ng/ml to a peak of 2.97± 0.57 ng/ml. Within 5 minutes of the pulse of LH,the secretion of Qstradiol (an exclusive productof the follicle) rose rapidly from a basal level of 0.75 ± 0.12 ng/miiij to reach a peak value of 2.16± 0.33 ng/min in about 30 minutes. In contrast,the secretion of progesterone from the corpus luteum,and the concentration of progesterone in the periph-eral plasma changed very little following the pulseof LH. The secretion of androstenedione, whicharises from the follicle and corpus luteum, in-creased from 3.03 ± 0.75 ng/min to 7.85 ± 1.78ng/min by 30 minutes after the pulse of LH. These findings indicate that the follicle, and pos-sibly the stroma, respond rapidly to episodicfluctuations in the concentration of LH and areprobably involved in the negative feedback loopbetween the ovary and the hypothalamic pi-tuitary system. The fluctuations in the secretion ofprogesterone from the corpus luteum, on the otherhand, are unrelated to pulses of LH. (Endocrinology 98: 1490,1976)" @default.
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- W1996046925 date "1976-06-01" @default.
- W1996046925 modified "2023-09-25" @default.
- W1996046925 title "Pulsatile Release of LH and Secretion of Ovarian Steroidsin Sheep During the Luteal Phase of the Estrous Cycle" @default.
- W1996046925 doi "https://doi.org/10.1210/endo-98-6-1490" @default.
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