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- W1996065618 abstract "Homopolymeric stretches of deoxyadenosine nucleotides (A's) on one strand of double-stranded DNA, referred to as poly(dA:dT) tracts or A-tracts, are overabundant in eukaryotic genomes. They have unusual structural, dynamic, and mechanical properties, and may resist sharp bending. Such unusual material properties, together with their overabundance in eukaryotes, raised the possibility that poly(dA:dT) tracts might function in eukaryotes to influence the organization of nucleosomes at many genomic regions. Recent genome-wide studies strongly confirm these ideas and suggest that these tracts play major roles in chromatin organization and genome function. Here we review what is known about poly(dA:dT) tracts and how they work." @default.
- W1996065618 created "2016-06-24" @default.
- W1996065618 creator A5012450539 @default.
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- W1996065618 date "2009-02-01" @default.
- W1996065618 modified "2023-10-11" @default.
- W1996065618 title "Poly(dA:dT) tracts: major determinants of nucleosome organization" @default.
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- W1996065618 doi "https://doi.org/10.1016/j.sbi.2009.01.004" @default.
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