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- W1996088675 abstract "Recent progress in structure-function studies of glycoprotein hormones has provided new insights into the molecular mechanisms of action of these hormones and has further supported the concept that physiological modulation of assembly, bioactivity, and clearance of these hormones is dependent on specific structural components. This review emphasizes current advances in the structure-function relationships of human TSH, which have contributed to further elucidation of common and hormone specific features within the glycoprotein hormones family. Novel strategies are now being applied to investigate the role of individual structural elements. The principks discovered in such studies are essential to understand the physiological regulation of hormone bioactivity and allow for the rational design of novel analogs with potential therapeutic applications." @default.
- W1996088675 created "2016-06-24" @default.
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- W1996088675 date "1996-10-01" @default.
- W1996088675 modified "2023-09-27" @default.
- W1996088675 title "Structure-function studies of human TSH" @default.
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- W1996088675 doi "https://doi.org/10.1016/s1043-2760(96)00129-4" @default.
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