FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1996090247> ?p ?o ?g. }

• W1996090247 endingPage "680" @default.
• W1996090247 startingPage "673" @default.
• W1996090247 abstract "The common receptor for neurotrophins, p75, has important roles in internalization and trafficking of neurotrophins along axons. Recent studies show that an astonishing array of proteins, including lectins, pathogens and neurotoxins, bind the p75 receptor, suggesting that they can hijack and utilize this receptor for trafficking between neuronal populations within the nervous system. Such pathogens include the neurologically important rabies viruses, prion proteins, beta-amyloid and possibly tetanus toxin. These proteins may hijack existing transport machineries designed to traffick neurotrophins, thus allowing the infiltration and distribution of pathogens and toxins among vulnerable neuronal populations with devastating effects, as seen in rabies, prion encephalopathies, Alzheimer's disease and tetanic muscle spasm. The discovery of an entry and transport machinery that is potentially shared between pathogens and neurotrophins sheds light ono trafficking systems in the nervous system and may assist the design of novel therapeutic avenues that prevent or slow the progression of diverse chronic and acute neurological disorders." @default.
• W1996090247 created "2016-06-24" @default.
• W1996090247 creator A5024090357 @default.
• W1996090247 creator A5044337676 @default.
• W1996090247 date "2003-02-01" @default.
• W1996090247 modified "2023-10-17" @default.
• W1996090247 title "Connecting the dots: trafficking of neurotrophins, lectins and diverse pathogens by binding to the neurotrophin receptor p75^NTR" @default.
• W1996090247 cites W1514296939 @default.
• W1996090247 cites W1525792378 @default.
• W1996090247 cites W1526459147 @default.
• W1996090247 cites W1540484053 @default.
• W1996090247 cites W1543517621 @default.
• W1996090247 cites W1565265443 @default.
• W1996090247 cites W1576690422 @default.
• W1996090247 cites W1590172087 @default.
• W1996090247 cites W1600856176 @default.
• W1996090247 cites W1964333027 @default.
• W1996090247 cites W1965072630 @default.
• W1996090247 cites W1966475047 @default.
• W1996090247 cites W1967336797 @default.
• W1996090247 cites W1970772856 @default.
• W1996090247 cites W1973035459 @default.
• W1996090247 cites W1974475508 @default.
• W1996090247 cites W1980179128 @default.
• W1996090247 cites W1983906385 @default.
• W1996090247 cites W1985822867 @default.
• W1996090247 cites W1986538583 @default.
• W1996090247 cites W1989081602 @default.
• W1996090247 cites W1989875198 @default.
• W1996090247 cites W1990804390 @default.
• W1996090247 cites W1991090581 @default.
• W1996090247 cites W1999770027 @default.
• W1996090247 cites W1999984945 @default.
• W1996090247 cites W2000469457 @default.
• W1996090247 cites W2002219529 @default.
• W1996090247 cites W2002813546 @default.
• W1996090247 cites W2005801157 @default.
• W1996090247 cites W2010258335 @default.
• W1996090247 cites W2011381918 @default.
• W1996090247 cites W2012299945 @default.
• W1996090247 cites W2021097827 @default.
• W1996090247 cites W2023830686 @default.
• W1996090247 cites W2029196209 @default.
• W1996090247 cites W2030662833 @default.
• W1996090247 cites W2030723260 @default.
• W1996090247 cites W2034656363 @default.
• W1996090247 cites W2035339855 @default.
• W1996090247 cites W2037953829 @default.
• W1996090247 cites W2048121291 @default.
• W1996090247 cites W2052559593 @default.
• W1996090247 cites W2056546860 @default.
• W1996090247 cites W2065482131 @default.
• W1996090247 cites W2069482942 @default.
• W1996090247 cites W2070813646 @default.
• W1996090247 cites W2071766765 @default.
• W1996090247 cites W2073543440 @default.
• W1996090247 cites W2074369656 @default.
• W1996090247 cites W2076432198 @default.
• W1996090247 cites W2077009055 @default.
• W1996090247 cites W2077897416 @default.
• W1996090247 cites W2078314172 @default.
• W1996090247 cites W2082022687 @default.
• W1996090247 cites W2082824466 @default.
• W1996090247 cites W2083358085 @default.
• W1996090247 cites W2083867490 @default.
• W1996090247 cites W2085337971 @default.
• W1996090247 cites W2087090756 @default.
• W1996090247 cites W2089124684 @default.
• W1996090247 cites W2090564186 @default.
• W1996090247 cites W2094765619 @default.
• W1996090247 cites W2096982709 @default.
• W1996090247 cites W2105012597 @default.
• W1996090247 cites W2111426823 @default.
• W1996090247 cites W2112089287 @default.
• W1996090247 cites W2118813298 @default.
• W1996090247 cites W2120594140 @default.
• W1996090247 cites W2122977798 @default.
• W1996090247 cites W2124054304 @default.
• W1996090247 cites W2130127829 @default.
• W1996090247 cites W2131388825 @default.
• W1996090247 cites W2132590272 @default.
• W1996090247 cites W2133740188 @default.
• W1996090247 cites W2136965814 @default.
• W1996090247 cites W2142819123 @default.
• W1996090247 cites W2144435898 @default.
• W1996090247 cites W2144652840 @default.
• W1996090247 cites W2146721301 @default.
• W1996090247 cites W2147213854 @default.
• W1996090247 cites W2151327803 @default.
• W1996090247 cites W2152735279 @default.
• W1996090247 cites W2154977175 @default.
• W1996090247 cites W2158349329 @default.
• W1996090247 cites W2161954641 @default.
• W1996090247 cites W2163376053 @default.
• W1996090247 cites W2164658118 @default.
• W1996090247 cites W2169915056 @default.
• W1996090247 cites W2414767482 @default.
• W1996090247 cites W4229510242 @default.

• next