FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1996096057> ?p ?o ?g. }

• W1996096057 endingPage "3692" @default.
• W1996096057 startingPage "3685" @default.
• W1996096057 abstract "The lack of an in vitro real-time osteoclast (OC) activity assay has hampered mechanistic studies of bone resorption. Such an assay is developed, employing a hydroxyapatite matrix impregnated with alkyl-capped silicon nanocrystals, which is capable of monitoring the time-course of resorption by single osteoclasts. Resorption of the matrix by OC releases the nanocrystals, which are internalized by the cell and detected as an increase in OC luminescence. This particular choice of nanocrystals is motivated by their bright pH-independent luminescence, proportional to concentration, and by their rapid uptake without cytotoxicity. In this in vitro assay, OCs are inhibited by calcitonin (CT) and methyl-β-cyclodextrin (MCD), and stimulated by receptor activator of nuclear factor kappa-B ligand (RANKL) in the expected manner. The kinetics of the assay exhibit a lag phase representing cell attachment and commencement of resorption processes, followed by a growth of cell luminescence intensity, and the whole time-course is satisfactorily described by the logistic equation." @default.
• W1996096057 created "2016-06-24" @default.
• W1996096057 creator A5019428130 @default.
• W1996096057 creator A5074571441 @default.
• W1996096057 creator A5085962396 @default.
• W1996096057 creator A5089069069 @default.
• W1996096057 creator A5054270221 @default.
• W1996096057 date "2013-05-06" @default.
• W1996096057 modified "2023-10-14" @default.
• W1996096057 title "Real-Time Activity Bioassay of Single Osteoclasts Using a Silicon Nanocrystal-Impregnated Artificial Matrix" @default.
• W1996096057 cites W1967502057 @default.
• W1996096057 cites W1969549366 @default.
• W1996096057 cites W1989498925 @default.
• W1996096057 cites W1999826236 @default.
• W1996096057 cites W2014220117 @default.
• W1996096057 cites W2019096884 @default.
• W1996096057 cites W2023071036 @default.
• W1996096057 cites W2025815021 @default.
• W1996096057 cites W2036165919 @default.
• W1996096057 cites W2036741442 @default.
• W1996096057 cites W2048386999 @default.
• W1996096057 cites W2051314302 @default.
• W1996096057 cites W2057935861 @default.
• W1996096057 cites W2058774752 @default.
• W1996096057 cites W2061740616 @default.
• W1996096057 cites W2063575064 @default.
• W1996096057 cites W2067152947 @default.
• W1996096057 cites W2067418101 @default.
• W1996096057 cites W2077386452 @default.
• W1996096057 cites W2089015855 @default.
• W1996096057 cites W2100507694 @default.
• W1996096057 cites W2118685639 @default.
• W1996096057 cites W2118699123 @default.
• W1996096057 cites W2120131660 @default.
• W1996096057 cites W2134221912 @default.
• W1996096057 cites W2140847067 @default.
• W1996096057 cites W2150401271 @default.
• W1996096057 cites W2331119574 @default.
• W1996096057 cites W2417966299 @default.
• W1996096057 doi "https://doi.org/10.1002/smll.201203184" @default.
• W1996096057 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23650249" @default.
• W1996096057 hasPublicationYear "2013" @default.
• W1996096057 type Work @default.
• W1996096057 sameAs 1996096057 @default.
• W1996096057 citedByCount "1" @default.
• W1996096057 countsByYear W19960960572022 @default.
• W1996096057 crossrefType "journal-article" @default.
• W1996096057 hasAuthorship W1996096057A5019428130 @default.
• W1996096057 hasAuthorship W1996096057A5054270221 @default.
• W1996096057 hasAuthorship W1996096057A5074571441 @default.
• W1996096057 hasAuthorship W1996096057A5085962396 @default.
• W1996096057 hasAuthorship W1996096057A5089069069 @default.
• W1996096057 hasBestOaLocation W19960960571 @default.
• W1996096057 hasConcept C106487976 @default.
• W1996096057 hasConcept C109316439 @default.
• W1996096057 hasConcept C12554922 @default.
• W1996096057 hasConcept C134018914 @default.
• W1996096057 hasConcept C146562846 @default.
• W1996096057 hasConcept C148869448 @default.
• W1996096057 hasConcept C170493617 @default.
• W1996096057 hasConcept C171250308 @default.
• W1996096057 hasConcept C175854130 @default.
• W1996096057 hasConcept C185592680 @default.
• W1996096057 hasConcept C192562407 @default.
• W1996096057 hasConcept C202751555 @default.
• W1996096057 hasConcept C2776033226 @default.
• W1996096057 hasConcept C2779428903 @default.
• W1996096057 hasConcept C43617362 @default.
• W1996096057 hasConcept C49040817 @default.
• W1996096057 hasConcept C55493867 @default.
• W1996096057 hasConcept C673006 @default.
• W1996096057 hasConcept C86803240 @default.
• W1996096057 hasConcept C88045685 @default.
• W1996096057 hasConceptScore W1996096057C106487976 @default.
• W1996096057 hasConceptScore W1996096057C109316439 @default.
• W1996096057 hasConceptScore W1996096057C12554922 @default.
• W1996096057 hasConceptScore W1996096057C134018914 @default.
• W1996096057 hasConceptScore W1996096057C146562846 @default.
• W1996096057 hasConceptScore W1996096057C148869448 @default.
• W1996096057 hasConceptScore W1996096057C170493617 @default.
• W1996096057 hasConceptScore W1996096057C171250308 @default.
• W1996096057 hasConceptScore W1996096057C175854130 @default.
• W1996096057 hasConceptScore W1996096057C185592680 @default.
• W1996096057 hasConceptScore W1996096057C192562407 @default.
• W1996096057 hasConceptScore W1996096057C202751555 @default.
• W1996096057 hasConceptScore W1996096057C2776033226 @default.
• W1996096057 hasConceptScore W1996096057C2779428903 @default.
• W1996096057 hasConceptScore W1996096057C43617362 @default.
• W1996096057 hasConceptScore W1996096057C49040817 @default.
• W1996096057 hasConceptScore W1996096057C55493867 @default.
• W1996096057 hasConceptScore W1996096057C673006 @default.
• W1996096057 hasConceptScore W1996096057C86803240 @default.
• W1996096057 hasConceptScore W1996096057C88045685 @default.
• W1996096057 hasIssue "21" @default.
• W1996096057 hasLocation W19960960571 @default.
• W1996096057 hasLocation W19960960572 @default.
• W1996096057 hasLocation W19960960573 @default.
• W1996096057 hasOpenAccess W1996096057 @default.

• next