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- W1996129612 abstract "Branchiomeric craniofacial muscles control feeding, breathing and facial expression. These muscles differ on multiple counts from all other skeletal muscles and originate in a progenitor cell population in pharyngeal mesoderm characterized by a common genetic program with an adjacent population of cardiac progenitor cells, the second heart field, that gives rise to much of the heart. The transcription factors and signaling molecules that trigger the myogenic program at sites of branchiomeric muscle formation are correspondingly distinct from those in somite-derived muscle progenitor cells. Here new insights into the regulatory hierarchies controlling branchiomeric myogenesis are discussed. Differences in embryological origin are reflected in the lineage, transcriptional program and proliferative and differentiation properties of branchiomeric muscle satellite cells. These recent findings have important implications for our understanding of the diverse myogenic strategies operative both in the embryo and adult and are of direct biomedical relevance to deciphering the mechanisms underlying the cause and progression of muscle restricted myopathies." @default.
- W1996129612 created "2016-06-24" @default.
- W1996129612 creator A5073557002 @default.
- W1996129612 date "2010-11-01" @default.
- W1996129612 modified "2023-10-14" @default.
- W1996129612 title "Core issues in craniofacial myogenesis" @default.
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- W1996129612 doi "https://doi.org/10.1016/j.yexcr.2010.04.029" @default.
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