Matches in SemOpenAlex for { <https://semopenalex.org/work/W1996149831> ?p ?o ?g. }
- W1996149831 endingPage "281" @default.
- W1996149831 startingPage "271" @default.
- W1996149831 abstract "The location of L-glutamate decarboxylase and gamma-aminobutyrate (GABA)-transaminase immunoreactivity in the superior cervical ganglion and in the coeliac-superior mesenteric ganglion complex of the rat was studied by an indirect immunofluorescence method and by immunoelectron microscopy, with specific antisera raised in rabbits against the corresponding enzymes. In light microscopy, several glutamate decarboxylase- or GABA-transaminase-immunoreactive principal nerve cells were detected in the superior cervical ganglion and coeliac-superior mesenteric ganglion complex. In addition, numerous small cells in both the superior cervical ganglion and coeliac-superior mesenteric ganglion complex showed intense immunoreactivity to glutamate decarboxylase or GABA-transaminase. The small cells were 10-20 micron in diameter and resembled in size and morphology the small intensely fluorescent cells. In consecutive sections, the small glutamate decarboxylase-immunoreactive cell clusters also showed immunoreactivity to tyrosine hydroxylase, suggesting that these cells contain the enzymes for both GABA and catecholamine synthesis. In the superior cervical ganglion and in the coeliac-superior mesenteric ganglion complex, GABA-transaminase immunoreactivity was also localized in fibre-like processes around and between the principal nerve cells, in nerve trunks traversing the ganglia, and around or in close contact with ganglionic blood vessels. Furthermore, GABA-transaminase immunoreactivity was observed in fibre-like structures close to the capsule of the ganglia. Division of the preganglionic nerve trunk of the superior cervical ganglion caused no detectable change in GABA-transaminase immunoreactivity in the ganglion. In immunoelectron microscopy of the superior cervical ganglion, GABA-transaminase immunoreactivity was localized in nerve fibres in association with neurotubules. A large number of GABA-transaminase labelled principal nerve cells were detected, containing immunoreactivity evenly distributed in their cytoplasm. GABA-transaminase immunoreactivity was also observed in satellite cells and their processes in the superior cervical ganglion. The present immunocytochemical results provide evidence that the rat sympathetic ganglia contain an intrinsic neuronal system showing histochemical markers for GABA synthesis and inactivation, but its functional role in the modulation of ganglionic neurotransmission remains to be established." @default.
- W1996149831 created "2016-06-24" @default.
- W1996149831 creator A5014800650 @default.
- W1996149831 creator A5027565314 @default.
- W1996149831 creator A5040819373 @default.
- W1996149831 creator A5056724127 @default.
- W1996149831 creator A5059139894 @default.
- W1996149831 date "1987-04-01" @default.
- W1996149831 modified "2023-09-26" @default.
- W1996149831 title "Localization of l-glutamate decarboxylase and GABA transaminase immunoreactivity in the sympathetic ganglia of the rat" @default.
- W1996149831 cites W124909345 @default.
- W1996149831 cites W1513299191 @default.
- W1996149831 cites W1598732229 @default.
- W1996149831 cites W166813605 @default.
- W1996149831 cites W1970296468 @default.
- W1996149831 cites W1971967360 @default.
- W1996149831 cites W1976514842 @default.
- W1996149831 cites W1981237842 @default.
- W1996149831 cites W1988692513 @default.
- W1996149831 cites W1990677788 @default.
- W1996149831 cites W1991411285 @default.
- W1996149831 cites W1995437664 @default.
- W1996149831 cites W1996066806 @default.
- W1996149831 cites W1996954690 @default.
- W1996149831 cites W1997378470 @default.
- W1996149831 cites W1999583152 @default.
- W1996149831 cites W2005349247 @default.
- W1996149831 cites W2006446305 @default.
- W1996149831 cites W2010488597 @default.
- W1996149831 cites W2022424210 @default.
- W1996149831 cites W2031887755 @default.
- W1996149831 cites W2034384673 @default.
- W1996149831 cites W2036566928 @default.
- W1996149831 cites W2037612483 @default.
- W1996149831 cites W2042048715 @default.
- W1996149831 cites W2055032793 @default.
- W1996149831 cites W2055374900 @default.
- W1996149831 cites W2057998213 @default.
- W1996149831 cites W2059485890 @default.
- W1996149831 cites W2060504338 @default.
- W1996149831 cites W2067225454 @default.
- W1996149831 cites W2074038910 @default.
- W1996149831 cites W2074090350 @default.
- W1996149831 cites W2081004543 @default.
- W1996149831 cites W2081301520 @default.
- W1996149831 cites W2082058331 @default.
- W1996149831 cites W2090362498 @default.
- W1996149831 cites W2113898169 @default.
- W1996149831 doi "https://doi.org/10.1016/0306-4522(87)90338-1" @default.
- W1996149831 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3299141" @default.
- W1996149831 hasPublicationYear "1987" @default.
- W1996149831 type Work @default.
- W1996149831 sameAs 1996149831 @default.
- W1996149831 citedByCount "32" @default.
- W1996149831 countsByYear W19961498312018 @default.
- W1996149831 countsByYear W19961498312019 @default.
- W1996149831 crossrefType "journal-article" @default.
- W1996149831 hasAuthorship W1996149831A5014800650 @default.
- W1996149831 hasAuthorship W1996149831A5027565314 @default.
- W1996149831 hasAuthorship W1996149831A5040819373 @default.
- W1996149831 hasAuthorship W1996149831A5056724127 @default.
- W1996149831 hasAuthorship W1996149831A5059139894 @default.
- W1996149831 hasConcept C105702510 @default.
- W1996149831 hasConcept C126322002 @default.
- W1996149831 hasConcept C134018914 @default.
- W1996149831 hasConcept C181199279 @default.
- W1996149831 hasConcept C204232928 @default.
- W1996149831 hasConcept C2777646271 @default.
- W1996149831 hasConcept C2778993773 @default.
- W1996149831 hasConcept C2781334511 @default.
- W1996149831 hasConcept C2993140218 @default.
- W1996149831 hasConcept C55493867 @default.
- W1996149831 hasConcept C71924100 @default.
- W1996149831 hasConcept C86803240 @default.
- W1996149831 hasConcept C9497952 @default.
- W1996149831 hasConceptScore W1996149831C105702510 @default.
- W1996149831 hasConceptScore W1996149831C126322002 @default.
- W1996149831 hasConceptScore W1996149831C134018914 @default.
- W1996149831 hasConceptScore W1996149831C181199279 @default.
- W1996149831 hasConceptScore W1996149831C204232928 @default.
- W1996149831 hasConceptScore W1996149831C2777646271 @default.
- W1996149831 hasConceptScore W1996149831C2778993773 @default.
- W1996149831 hasConceptScore W1996149831C2781334511 @default.
- W1996149831 hasConceptScore W1996149831C2993140218 @default.
- W1996149831 hasConceptScore W1996149831C55493867 @default.
- W1996149831 hasConceptScore W1996149831C71924100 @default.
- W1996149831 hasConceptScore W1996149831C86803240 @default.
- W1996149831 hasConceptScore W1996149831C9497952 @default.
- W1996149831 hasIssue "1" @default.
- W1996149831 hasLocation W19961498311 @default.
- W1996149831 hasLocation W19961498312 @default.
- W1996149831 hasOpenAccess W1996149831 @default.
- W1996149831 hasPrimaryLocation W19961498311 @default.
- W1996149831 hasRelatedWork W1984077238 @default.
- W1996149831 hasRelatedWork W1988863515 @default.
- W1996149831 hasRelatedWork W1996030698 @default.
- W1996149831 hasRelatedWork W1996149831 @default.
- W1996149831 hasRelatedWork W2042167375 @default.