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• W1996154003 abstract "What is known and objective Health economic evaluation (HEE) is increasingly used in healthcare decision-making on the allocation of limited resources in national healthcare systems. Although the methods used for HEE vary in different countries, all economic evaluations address two questions: Are limited resources used optimally? Is value for money achieved in their use? Our objective is to explain some fundamental concepts in HEE and how these concepts are adapted in different countries, notably in Germany. Methods We performed a bibliographic search to identify existing methods of health economic evaluation of new drugs used by the official agencies of 11 countries (Austria, Australia, Canada, Finland, France, the Netherlands, Norway, New Zealand, Sweden, the United States and England and Wales) and compared them with that used by the German national agency IQWiG. Results and discussion All countries considered follow internationally established standards of HEE. The majority of countries, including Germany, utilize primary outcome parameters such as disease-related morbidity and mortality for assessing relative efficacy and effectiveness. The most frequently recommended form of health economic evaluation is the cost–utility analysis (CUA). The German IQWIG is the only HTA body to use the cost–benefit concept of ‘efficiency frontier’ in its assessment. What is new and conclusion While the core principles of HEE are the same worldwide, there is a lack of harmonization in the details. This requires resource-consuming adaptations in the analyses to meet different national requirements. We describe the core principles of HEE as a common basis for further discussions by all stakeholders." @default.
• W1996154003 created "2016-06-24" @default.
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• W1996154003 date "2013-04-26" @default.
• W1996154003 modified "2023-10-04" @default.
• W1996154003 title "International standards for health economic evaluation with a focus on the German approach" @default.
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• W1996154003 doi "https://doi.org/10.1111/jcpt.12043" @default.
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