FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1996160109> ?p ?o ?g. }

• W1996160109 endingPage "712" @default.
• W1996160109 startingPage "701" @default.
• W1996160109 abstract "Iodine is a trace element that is essential for the synthesis of thyroid hormone. Both chronic iodine deficiency and iodine excess have been associated with hypertrophy and hyperplasia of follicular cells, attributed to excessive secretion of TSH. This may be associated to thyroid cancer risk, particularly in women. Experimental studies have documented thyroid cancer induction by elevation of endogenous TSH, although in a small number of animals. Iodine deficiency associated with carcinogenic agents and chemical mutagens will result in a higher incidence of thyroid malignancy. Inadequate low iodine intake will result in increased TSH stimulation, increased thyroid cell responsiveness to TSH, increased thyroid cell EGF-induced proliferation, decreased TGFbeta 1 production and increased angiogenesis, all phenomena related to promotion of tumor growth. Epidemiological studies associating iodine intake and thyroid cancer led to controversial and conflicting results. There is no doubt that introduction of universal iodine prophylaxis in population previously in chronic iodine-deficiency leads to a changing pattern of more prevalent papillary thyroid cancer and declining of follicular thyroid cancer. Also anaplastic thyroid cancer is practically not seen after years of iodine supplementation. Iodine excess has also been indicated as a possible nutritional factor in the prevalence of differentiated thyroid cancer in Iceland, Hawaii and, more recently, in China. In conclusion: available evidence from animal experiments, epidemiological studies and iodine prophylaxis has demonstrated a shift towards a rise in papillary carcinoma, but no clear relationship between overall thyroid cancer incidence and iodine intake." @default.
• W1996160109 created "2016-06-24" @default.
• W1996160109 creator A5073526759 @default.
• W1996160109 creator A5086626649 @default.
• W1996160109 date "2007-07-01" @default.
• W1996160109 modified "2023-10-16" @default.
• W1996160109 title "Relevance of iodine intake as a reputed predisposing factor for thyroid cancer" @default.
• W1996160109 cites W1583392323 @default.
• W1996160109 cites W1819609506 @default.
• W1996160109 cites W1965830870 @default.
• W1996160109 cites W1967360498 @default.
• W1996160109 cites W1968153880 @default.
• W1996160109 cites W1983680839 @default.
• W1996160109 cites W1991121868 @default.
• W1996160109 cites W1994211760 @default.
• W1996160109 cites W1994419134 @default.
• W1996160109 cites W1995987532 @default.
• W1996160109 cites W2005718666 @default.
• W1996160109 cites W2006434214 @default.
• W1996160109 cites W2011002725 @default.
• W1996160109 cites W2018486838 @default.
• W1996160109 cites W2019040788 @default.
• W1996160109 cites W2020525179 @default.
• W1996160109 cites W2034602546 @default.
• W1996160109 cites W2034853497 @default.
• W1996160109 cites W2038436387 @default.
• W1996160109 cites W2041394824 @default.
• W1996160109 cites W2042743000 @default.
• W1996160109 cites W2045882084 @default.
• W1996160109 cites W2053244541 @default.
• W1996160109 cites W2053442975 @default.
• W1996160109 cites W2059440917 @default.
• W1996160109 cites W2059650341 @default.
• W1996160109 cites W2060703328 @default.
• W1996160109 cites W2063031160 @default.
• W1996160109 cites W2070429012 @default.
• W1996160109 cites W2073052224 @default.
• W1996160109 cites W2074775856 @default.
• W1996160109 cites W2080240500 @default.
• W1996160109 cites W2081581129 @default.
• W1996160109 cites W2081934370 @default.
• W1996160109 cites W2087905452 @default.
• W1996160109 cites W2089357436 @default.
• W1996160109 cites W2090609097 @default.
• W1996160109 cites W2091059825 @default.
• W1996160109 cites W2091337691 @default.
• W1996160109 cites W2094304886 @default.
• W1996160109 cites W2098692142 @default.
• W1996160109 cites W2105460908 @default.
• W1996160109 cites W2106419483 @default.
• W1996160109 cites W2107516434 @default.
• W1996160109 cites W2108539588 @default.
• W1996160109 cites W2119097855 @default.
• W1996160109 cites W2120224038 @default.
• W1996160109 cites W2120428357 @default.
• W1996160109 cites W2124007666 @default.
• W1996160109 cites W2124443627 @default.
• W1996160109 cites W2131601788 @default.
• W1996160109 cites W2134724012 @default.
• W1996160109 cites W2136314611 @default.
• W1996160109 cites W2139950625 @default.
• W1996160109 cites W2147483181 @default.
• W1996160109 cites W2148261989 @default.
• W1996160109 cites W2150765525 @default.
• W1996160109 cites W2151747343 @default.
• W1996160109 cites W2154616861 @default.
• W1996160109 cites W2159339914 @default.
• W1996160109 cites W2159797128 @default.
• W1996160109 cites W2161319846 @default.
• W1996160109 cites W2166086645 @default.
• W1996160109 cites W4255232803 @default.
• W1996160109 doi "https://doi.org/10.1590/s0004-27302007000500007" @default.
• W1996160109 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17891233" @default.
• W1996160109 hasPublicationYear "2007" @default.
• W1996160109 type Work @default.
• W1996160109 sameAs 1996160109 @default.
• W1996160109 citedByCount "72" @default.
• W1996160109 countsByYear W19961601092012 @default.
• W1996160109 countsByYear W19961601092013 @default.
• W1996160109 countsByYear W19961601092014 @default.
• W1996160109 countsByYear W19961601092015 @default.
• W1996160109 countsByYear W19961601092016 @default.
• W1996160109 countsByYear W19961601092017 @default.
• W1996160109 countsByYear W19961601092018 @default.
• W1996160109 countsByYear W19961601092019 @default.
• W1996160109 countsByYear W19961601092020 @default.
• W1996160109 countsByYear W19961601092021 @default.
• W1996160109 countsByYear W19961601092022 @default.
• W1996160109 crossrefType "journal-article" @default.
• W1996160109 hasAuthorship W1996160109A5073526759 @default.
• W1996160109 hasAuthorship W1996160109A5086626649 @default.
• W1996160109 hasBestOaLocation W19961601091 @default.
• W1996160109 hasConcept C121608353 @default.
• W1996160109 hasConcept C126322002 @default.
• W1996160109 hasConcept C134018914 @default.
• W1996160109 hasConcept C178790620 @default.
• W1996160109 hasConcept C185592680 @default.
• W1996160109 hasConcept C2778057883 @default.

• next