Matches in SemOpenAlex for { <https://semopenalex.org/work/W1996174328> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W1996174328 abstract "Brn-3a and Brn-3b are closely related members of the POU family of transcription factors which have opposite effects on the activity of target promoters. When mouse or human neuroblastoma cells are induced to differentiate to a non-dividing phenotype bearing numerous neuronal processes, the levels of Brn-3a rise dramatically whilst Brn-3b levels fall. Inhibition of Brn-3a expression using an antisense approach or over-expression of Brn-3b, prevents the differentiation of neuroblastoma cells in response to stimuli which normally induce it. Conversely, over-expression of Brn-3a induces differentiation in the absence of such stimuli. Hence the balance between Brn-3a and Brn-3b plays a key role in regulating neuroblastoma differentiation via the activation by Brn-3a or repression by Brn-3b of specific genes whose protein products are required for this process." @default.
- W1996174328 created "2016-06-24" @default.
- W1996174328 creator A5059598912 @default.
- W1996174328 date "1997-06-01" @default.
- W1996174328 modified "2023-09-27" @default.
- W1996174328 title "Regulation of neuroblastoma growth and differentiation by the POU family transcription factors Brn-3a and Brn-3b (Review)" @default.
- W1996174328 doi "https://doi.org/10.3892/ijo.10.6.1133" @default.
- W1996174328 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21533495" @default.
- W1996174328 hasPublicationYear "1997" @default.
- W1996174328 type Work @default.
- W1996174328 sameAs 1996174328 @default.
- W1996174328 citedByCount "1" @default.
- W1996174328 crossrefType "journal-article" @default.
- W1996174328 hasAuthorship W1996174328A5059598912 @default.
- W1996174328 hasConcept C104317684 @default.
- W1996174328 hasConcept C121587040 @default.
- W1996174328 hasConcept C127716648 @default.
- W1996174328 hasConcept C148738053 @default.
- W1996174328 hasConcept C196287685 @default.
- W1996174328 hasConcept C2776715637 @default.
- W1996174328 hasConcept C2781018059 @default.
- W1996174328 hasConcept C29537977 @default.
- W1996174328 hasConcept C502942594 @default.
- W1996174328 hasConcept C54355233 @default.
- W1996174328 hasConcept C81885089 @default.
- W1996174328 hasConcept C86339819 @default.
- W1996174328 hasConcept C86803240 @default.
- W1996174328 hasConcept C95444343 @default.
- W1996174328 hasConceptScore W1996174328C104317684 @default.
- W1996174328 hasConceptScore W1996174328C121587040 @default.
- W1996174328 hasConceptScore W1996174328C127716648 @default.
- W1996174328 hasConceptScore W1996174328C148738053 @default.
- W1996174328 hasConceptScore W1996174328C196287685 @default.
- W1996174328 hasConceptScore W1996174328C2776715637 @default.
- W1996174328 hasConceptScore W1996174328C2781018059 @default.
- W1996174328 hasConceptScore W1996174328C29537977 @default.
- W1996174328 hasConceptScore W1996174328C502942594 @default.
- W1996174328 hasConceptScore W1996174328C54355233 @default.
- W1996174328 hasConceptScore W1996174328C81885089 @default.
- W1996174328 hasConceptScore W1996174328C86339819 @default.
- W1996174328 hasConceptScore W1996174328C86803240 @default.
- W1996174328 hasConceptScore W1996174328C95444343 @default.
- W1996174328 hasLocation W19961743281 @default.
- W1996174328 hasLocation W19961743282 @default.
- W1996174328 hasOpenAccess W1996174328 @default.
- W1996174328 hasPrimaryLocation W19961743281 @default.
- W1996174328 hasRelatedWork W1616174717 @default.
- W1996174328 hasRelatedWork W182463778 @default.
- W1996174328 hasRelatedWork W1964116972 @default.
- W1996174328 hasRelatedWork W1976272896 @default.
- W1996174328 hasRelatedWork W2021471413 @default.
- W1996174328 hasRelatedWork W2024706596 @default.
- W1996174328 hasRelatedWork W2027884200 @default.
- W1996174328 hasRelatedWork W2038434907 @default.
- W1996174328 hasRelatedWork W2040680836 @default.
- W1996174328 hasRelatedWork W2068177691 @default.
- W1996174328 hasRelatedWork W2069480390 @default.
- W1996174328 hasRelatedWork W2079071443 @default.
- W1996174328 hasRelatedWork W2089645716 @default.
- W1996174328 hasRelatedWork W2094896662 @default.
- W1996174328 hasRelatedWork W2104199930 @default.
- W1996174328 hasRelatedWork W2124586487 @default.
- W1996174328 hasRelatedWork W2126144031 @default.
- W1996174328 hasRelatedWork W2140279459 @default.
- W1996174328 hasRelatedWork W2149139293 @default.
- W1996174328 hasRelatedWork W2336452721 @default.
- W1996174328 isParatext "false" @default.
- W1996174328 isRetracted "false" @default.
- W1996174328 magId "1996174328" @default.
- W1996174328 workType "article" @default.