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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1996204711> ?p ?o ?g. }

• W1996204711 endingPage "5866" @default.
• W1996204711 startingPage "5864" @default.
• W1996204711 abstract "A derivative of rhodamine 110 has been designed and assessed as a probe for cytochrome P450 activity. This probe is the first to utilize a ‘trimethyl lock’ that is triggered by cleavage of an ether bond. In vitro, fluorescence was manifested by the CYP1A1 isozyme with kcat/KM = 8.8 × 103 M−1 s−1 and KM = 0.09 μM. In cellulo, the probe revealed the induction of cytochrome P450 activity by the carcinogen 2,3,7,8-tetrachlorodibenzo-p-dioxin, and its repression by the chemoprotectant resveratrol." @default.
• W1996204711 created "2016-06-24" @default.
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• W1996204711 date "2008-11-01" @default.
• W1996204711 modified "2023-10-18" @default.
• W1996204711 title "A highly sensitive fluorogenic probe for cytochrome P450 activity in live cells" @default.
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• W1996204711 doi "https://doi.org/10.1016/j.bmcl.2008.06.015" @default.
• W1996204711 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2586036" @default.
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