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- W1996226533 abstract "The cytotoxicity of various dilutions of sodium hypochlorite was evaluated using three independent biological models. Dilutions as low as 1:1000 caused complete hemolysis of RBC's in vitro. Undiluted and 1:10 dilutions produced moderate to severe irritation to rabbit eyes which healed after 24 to 48 h. Intradermal injections of undiluted, 1:1, 1:2, and 1:4 dilutions of NaOCl produced skin ulcerations following intradermal injections. Although the use of 5% NaOCl for biomechanical preparation of root canals is a clinically acceptable and highly effective procedure, it must be used judiciously and with great caution to prevent it from reaching the periapex where it can elicit severe inflammatory reactions." @default.
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- W1996226533 date "1985-12-01" @default.
- W1996226533 modified "2023-10-14" @default.
- W1996226533 title "Cytotoxic effects of NaOCl on vital tissue" @default.
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- W1996226533 doi "https://doi.org/10.1016/s0099-2399(85)80197-7" @default.
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