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- W1996227112 abstract "Winter flounder (Pseudopleuronectes americanus) were sampled in summer 1989 and 1990 in Sydney Harbour, Nova Scotia, along a gradient of sediment polynuclear aromatic hydrocarbon (PAH) concentrations arising from industrial contamination; an uncontaminated bay nearby was used as a reference site. Hepatic mono-oxygenase activity, estimated by measurements of catalytic activity and by immunochemical analysis of cytochrome P-450 1A, increased with sediment PAH concentrations; the extent of induction between the reference and the most contaminated sites ranged up to 50-fold. Cyanoethoxycoumarin O-de-ethylase activity was at least as sensitive an indicator of mono-oxygenase induction as ethoxyresorufin O-de-ethylase or benzo(a)pyrene hydroxylase, and all three enzyme activities were well correlated with cytochrome P-450 1A concentrations and with sediment PAH concentrations." @default.
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- W1996227112 date "1994-01-01" @default.
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- W1996227112 title "Liver microsomal mono-oxygenase induction in winter flounder (Pseudopleuronectes americanus) from a gradient of sediment PAH concentrations at Sydney Harbour, Nova Scotia" @default.
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- W1996227112 doi "https://doi.org/10.1016/0141-1136(94)90055-8" @default.
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