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- W1996242530 abstract "1.1. The motor effect of the α2 adrenoreceptor antagonist, idazoxan, was compared to that of L-dopa in MPTP-treated monkeys.2.2. Idazoxan 2.0 mg/kg improved parkinsonian motor abnormalities which was comparable to the effects of a minimal effective dose of L-dopa.3.3. At 2.0 and 5.0 mg/kg, the parkinsonian rigidity was the item most frequently alleviated by idazoxan (respectively 63.6% and 68.2%).4.4. These findings provide support for the therapeutic utility of α2 antagonists in the treatment of Parkinson's disease." @default.
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- W1996242530 date "2004-09-01" @default.
- W1996242530 modified "2023-09-25" @default.
- W1996242530 title "Obésité et pathologie cardiovasculaire" @default.
- W1996242530 cites W2017221955 @default.
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- W1996242530 doi "https://doi.org/10.1016/s1261-694x(04)73426-4" @default.
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