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• W1996286769 abstract "A new strain that produced a lipase capable of enantioselectively hydrolyzing the ethyl ester of (R)-flurbiprofen was isolated from soil samples and identified as Bacillus cereus C71. The optimal temperature and pH for the hydrolysis reaction with resting cells were 35°C and 8.0, respectively. The surfactant Tween-40 enhanced the reaction rate and enantioselectivity. A small-scale production of (R)-flurbiprofen was conducted with 10 mmol L−1 substrate solution under the optimum conditions. After 36 h of reaction, 50% of the initial flurbiprofen ethyl ester was hydrolyzed to (R)-flurbiprofen with an enantiomeric excess (eep) of 96%, and an enantiomeric ratio (E) of >100. The cells could be reused and retained 60% of initial activity after recycling for six times." @default.
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• W1996286769 date "2007-01-01" @default.
• W1996286769 modified "2023-10-16" @default.
• W1996286769 title "Preparation of enantiopure (R)-flurbiprofen catalyzed by a newly isolatedBacillus cereusC71" @default.
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• W1996286769 doi "https://doi.org/10.1080/10242420600792250" @default.
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