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- W1996286799 abstract "A series of optically pure β-amino ketones have been synthesized in high enantioselectivities (ee > 99%) by Rh-DuanPhos-catalyzed asymmetric hydrogenation of readily prepared β-keto enamides. Further reduction of these β-amino ketones with hydrogen and Pd/C leads to the formation of a variety of protected enantiomerically pure γ-aryl amines (ee > 99%), which are key building blocks in many bioactive molecules." @default.
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- W1996286799 date "2010-12-09" @default.
- W1996286799 modified "2023-10-18" @default.
- W1996286799 title "Enantioselective Synthesis of Optically Pure β-Amino Ketones and γ-Aryl Amines by Rh-Catalyzed Asymmetric Hydrogenation" @default.
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- W1996286799 doi "https://doi.org/10.1021/jo102091f" @default.
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