Matches in SemOpenAlex for { <https://semopenalex.org/work/W1996296942> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W1996296942 abstract "Although accelerated partial breast irradiation (APBI) as the sole radiation modality after lumpectomy has shown promising results for select breast cancer patients, published experiences thus far have provided limited information on treatment planning methodology and quality assurance measures. A novel three-dimensional computed tomography (CT)-based treatment planning method for accurate delineation and geometric coverage of the target volume is presented. A correlation between treatment volume and irradiation time has also been studied for quality assurance purposes.Between May 2002 and January 2003, 50 consecutive patients underwent an image-guided interstitial implant followed by CT-based treatment planning and were subsequently treated with APBI with a high-dose-rate (HDR) brachytherapy remote afterloader. Target volume was defined as the lumpectomy cavity +2 cm margin modified to >/=5 mm to the skin surface. Catheter reconstruction, geometric optimization, and manual adjustment of irradiation time were done to optimally cover the target volume while minimizing hot spots. Dose homogeneity index (DHI) and percent of target volume receiving 100% of the prescription dose (32 Gy in 8 fractions or 34 Gy in 10 fractions) was determined. Additionally, the correlation between the treatment volume and irradiation time, source strength, and dose was then analyzed for manual verification of the HDR computer calculation.In all cases, the lumpectomy cavity was covered 100%. Target volume coverage was excellent with a median of 96%, and DHI had a median value of 0.7. For each plan, source strength times the treatment time for every unit of prescribed dose had an excellent agreement of +/-7% to the Manchester volume implant table corrected for modern units.CT-based treatment planning allowed excellent visualization of the lumpectomy cavity and normal structures, thereby improving target volume delineation and optimal coverage, relative to conventional orthogonal film dosimetry. Using the Manchester volume implant table calculated irradiation time can be used as quality assurance for the HDR computed time. Thus dosimetric quality assurance and adequate target volume coverage can be concurrently confirmed, allowing prospective evaluation and optimization of implants." @default.
- W1996296942 created "2016-06-24" @default.
- W1996296942 creator A5013903847 @default.
- W1996296942 creator A5016500631 @default.
- W1996296942 creator A5038635004 @default.
- W1996296942 creator A5049776168 @default.
- W1996296942 creator A5063272714 @default.
- W1996296942 date "2004-07-01" @default.
- W1996296942 modified "2023-10-16" @default.
- W1996296942 title "3D CT–based high-dose-rate breast brachytherapy implants: treatment planning and quality assurance" @default.
- W1996296942 cites W1973962349 @default.
- W1996296942 cites W1985656848 @default.
- W1996296942 cites W1995611063 @default.
- W1996296942 cites W1997095021 @default.
- W1996296942 cites W2039936657 @default.
- W1996296942 cites W2048449316 @default.
- W1996296942 cites W2087974488 @default.
- W1996296942 cites W2089645622 @default.
- W1996296942 cites W2110026602 @default.
- W1996296942 doi "https://doi.org/10.1016/j.ijrobp.2004.03.030" @default.
- W1996296942 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15234059" @default.
- W1996296942 hasPublicationYear "2004" @default.
- W1996296942 type Work @default.
- W1996296942 sameAs 1996296942 @default.
- W1996296942 citedByCount "73" @default.
- W1996296942 countsByYear W19962969422012 @default.
- W1996296942 countsByYear W19962969422013 @default.
- W1996296942 countsByYear W19962969422014 @default.
- W1996296942 countsByYear W19962969422015 @default.
- W1996296942 countsByYear W19962969422016 @default.
- W1996296942 countsByYear W19962969422017 @default.
- W1996296942 countsByYear W19962969422019 @default.
- W1996296942 countsByYear W19962969422020 @default.
- W1996296942 crossrefType "journal-article" @default.
- W1996296942 hasAuthorship W1996296942A5013903847 @default.
- W1996296942 hasAuthorship W1996296942A5016500631 @default.
- W1996296942 hasAuthorship W1996296942A5038635004 @default.
- W1996296942 hasAuthorship W1996296942A5049776168 @default.
- W1996296942 hasAuthorship W1996296942A5063272714 @default.
- W1996296942 hasConcept C104293457 @default.
- W1996296942 hasConcept C106436119 @default.
- W1996296942 hasConcept C121608353 @default.
- W1996296942 hasConcept C126322002 @default.
- W1996296942 hasConcept C126838900 @default.
- W1996296942 hasConcept C142724271 @default.
- W1996296942 hasConcept C201645570 @default.
- W1996296942 hasConcept C2777416452 @default.
- W1996296942 hasConcept C2777757722 @default.
- W1996296942 hasConcept C2778618615 @default.
- W1996296942 hasConcept C2779572924 @default.
- W1996296942 hasConcept C2989005 @default.
- W1996296942 hasConcept C509974204 @default.
- W1996296942 hasConcept C530470458 @default.
- W1996296942 hasConcept C71924100 @default.
- W1996296942 hasConceptScore W1996296942C104293457 @default.
- W1996296942 hasConceptScore W1996296942C106436119 @default.
- W1996296942 hasConceptScore W1996296942C121608353 @default.
- W1996296942 hasConceptScore W1996296942C126322002 @default.
- W1996296942 hasConceptScore W1996296942C126838900 @default.
- W1996296942 hasConceptScore W1996296942C142724271 @default.
- W1996296942 hasConceptScore W1996296942C201645570 @default.
- W1996296942 hasConceptScore W1996296942C2777416452 @default.
- W1996296942 hasConceptScore W1996296942C2777757722 @default.
- W1996296942 hasConceptScore W1996296942C2778618615 @default.
- W1996296942 hasConceptScore W1996296942C2779572924 @default.
- W1996296942 hasConceptScore W1996296942C2989005 @default.
- W1996296942 hasConceptScore W1996296942C509974204 @default.
- W1996296942 hasConceptScore W1996296942C530470458 @default.
- W1996296942 hasConceptScore W1996296942C71924100 @default.
- W1996296942 hasLocation W19962969421 @default.
- W1996296942 hasLocation W19962969422 @default.
- W1996296942 hasOpenAccess W1996296942 @default.
- W1996296942 hasPrimaryLocation W19962969421 @default.
- W1996296942 hasRelatedWork W1970665426 @default.
- W1996296942 hasRelatedWork W2062630704 @default.
- W1996296942 hasRelatedWork W2123010794 @default.
- W1996296942 hasRelatedWork W2340709279 @default.
- W1996296942 hasRelatedWork W2470940109 @default.
- W1996296942 hasRelatedWork W2795689053 @default.
- W1996296942 hasRelatedWork W2936237764 @default.
- W1996296942 hasRelatedWork W2974148763 @default.
- W1996296942 hasRelatedWork W2988127320 @default.
- W1996296942 hasRelatedWork W3120456031 @default.
- W1996296942 isParatext "false" @default.
- W1996296942 isRetracted "false" @default.
- W1996296942 magId "1996296942" @default.
- W1996296942 workType "article" @default.