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- W1996326847 endingPage "407" @default.
- W1996326847 startingPage "400" @default.
- W1996326847 abstract "All pathogenic microorganisms have in common that they need to feed on nutrients available from their host. Therefore, the specific interruption of metabolic pathways is a promising approach which could lead to the discovery of new antimicrobial drugs. However, nutrient availability strongly varies in respect to the infected host niche and pathogens may possess different strategies to acquire nutrients. This review focuses on the differences in regulation and use of key metabolic pathways during infection by pathogenic fungi, especially in the filamentous fungus Aspergillus fumigatus and the dimorphic yeast Candida albicans. Besides universal metabolic pathways, emphasis is given on pathways, which are absent in humans and might, therefore, suit as antifungal drug targets. Niche-specific nutrient availability and different physiological strategies complicate the identification of metabolic pathways, which are essential for all pathogens at each step of the infection process." @default.
- W1996326847 created "2016-06-24" @default.
- W1996326847 creator A5000719236 @default.
- W1996326847 creator A5022395132 @default.
- W1996326847 creator A5025312880 @default.
- W1996326847 date "2011-06-01" @default.
- W1996326847 modified "2023-09-24" @default.
- W1996326847 title "Nutrient acquisition by pathogenic fungi: Nutrient availability, pathway regulation, and differences in substrate utilization" @default.
- W1996326847 cites W1491021866 @default.
- W1996326847 cites W1507486726 @default.
- W1996326847 cites W1599051410 @default.
- W1996326847 cites W1647692986 @default.
- W1996326847 cites W1804531429 @default.
- W1996326847 cites W1862569349 @default.
- W1996326847 cites W187623135 @default.
- W1996326847 cites W1905945789 @default.
- W1996326847 cites W1909491037 @default.
- W1996326847 cites W1935518068 @default.
- W1996326847 cites W1942410765 @default.
- W1996326847 cites W1963672691 @default.
- W1996326847 cites W1967254719 @default.
- W1996326847 cites W1968507818 @default.
- W1996326847 cites W1969961597 @default.
- W1996326847 cites W1970770879 @default.
- W1996326847 cites W1970981516 @default.
- W1996326847 cites W1975312395 @default.
- W1996326847 cites W1976906282 @default.
- W1996326847 cites W1977880141 @default.
- W1996326847 cites W1983730914 @default.
- W1996326847 cites W1986207589 @default.
- W1996326847 cites W1986342700 @default.
- W1996326847 cites W1995155209 @default.
- W1996326847 cites W1997090665 @default.
- W1996326847 cites W1997290272 @default.
- W1996326847 cites W1999126415 @default.
- W1996326847 cites W2008888079 @default.
- W1996326847 cites W2009869521 @default.
- W1996326847 cites W2010747482 @default.
- W1996326847 cites W2011615854 @default.
- W1996326847 cites W2013686234 @default.
- W1996326847 cites W2016375744 @default.
- W1996326847 cites W2019398589 @default.
- W1996326847 cites W2021009407 @default.
- W1996326847 cites W2021388084 @default.
- W1996326847 cites W2025140569 @default.
- W1996326847 cites W2025269616 @default.
- W1996326847 cites W2025574234 @default.
- W1996326847 cites W2029173147 @default.
- W1996326847 cites W2030021883 @default.
- W1996326847 cites W2033493201 @default.
- W1996326847 cites W2043365114 @default.
- W1996326847 cites W2047484977 @default.
- W1996326847 cites W2054715340 @default.
- W1996326847 cites W2058090371 @default.
- W1996326847 cites W2059382856 @default.
- W1996326847 cites W2072764750 @default.
- W1996326847 cites W2077797584 @default.
- W1996326847 cites W2078806355 @default.
- W1996326847 cites W2079390987 @default.
- W1996326847 cites W2084021973 @default.
- W1996326847 cites W2085373613 @default.
- W1996326847 cites W2085406609 @default.
- W1996326847 cites W2086926679 @default.
- W1996326847 cites W2088109531 @default.
- W1996326847 cites W2089021764 @default.
- W1996326847 cites W2094230873 @default.
- W1996326847 cites W2095906727 @default.
- W1996326847 cites W2103352005 @default.
- W1996326847 cites W2106551743 @default.
- W1996326847 cites W2107810493 @default.
- W1996326847 cites W2109757903 @default.
- W1996326847 cites W2109962249 @default.
- W1996326847 cites W2110874942 @default.
- W1996326847 cites W2111013857 @default.
- W1996326847 cites W2111656780 @default.
- W1996326847 cites W2112659611 @default.
- W1996326847 cites W2116213013 @default.
- W1996326847 cites W2116275559 @default.
- W1996326847 cites W2118736387 @default.
- W1996326847 cites W2118902193 @default.
- W1996326847 cites W2119502295 @default.
- W1996326847 cites W2119993819 @default.
- W1996326847 cites W2123870108 @default.
- W1996326847 cites W2124814621 @default.
- W1996326847 cites W2125605543 @default.
- W1996326847 cites W2127691252 @default.
- W1996326847 cites W2131942193 @default.
- W1996326847 cites W2132171565 @default.
- W1996326847 cites W2133607159 @default.
- W1996326847 cites W2135741693 @default.
- W1996326847 cites W2137221290 @default.
- W1996326847 cites W2137626431 @default.
- W1996326847 cites W2139958361 @default.
- W1996326847 cites W2141612833 @default.
- W1996326847 cites W2142889585 @default.
- W1996326847 cites W2144526814 @default.
- W1996326847 cites W2144956287 @default.
- W1996326847 cites W2145517314 @default.