Matches in SemOpenAlex for { <https://semopenalex.org/work/W1996344434> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W1996344434 endingPage "1399" @default.
- W1996344434 startingPage "1387" @default.
- W1996344434 abstract "Abstract The chemical composition and conformation of ligand immobilized on bilirubin adsorbent have been proposed as the key factors to determine the affinity and specificity for bilirubin in patients' plasma. However, up to now, the effects of ligand composition on bilirubin removal are not clear. In this study, we selected human serum albumin (HSA), long carbolic chain and amino groups as the functional groups of ligand immobilized on Sepharose CL‐4B to discuss the effects. The results showed that amino groups and hydrophobic carbonic chains could be very important factors to adsorb bilirubin conjugated with albumin. The contribution of HSA to the adsorption may be owing to its dimensional obstruction for macromolecules approaching, thereby nonspecific adsorption was decreased in plasma. The adsorption capacity for bilirubin increased obviously with the rise of initial concentration of bilirubin in plasma. The adsorption capacity was 7.52 mg/mL gel for bilirubin in albumin phosphate buffer (pH 7.0) with bilirubin concentration of 377 mg/L, while it only got to 3.64 mg/mL in human plasma at the same concentration. The adsorption microenvironment with pH 7.0–8.0, higher temperature (30–40°C) and lower ionic strength were beneficial to the bilirubin adsorption." @default.
- W1996344434 created "2016-06-24" @default.
- W1996344434 creator A5003315472 @default.
- W1996344434 creator A5010942938 @default.
- W1996344434 creator A5016808440 @default.
- W1996344434 creator A5073529218 @default.
- W1996344434 date "2005-05-01" @default.
- W1996344434 modified "2023-10-14" @default.
- W1996344434 title "Synthesis and Characterization of Novel Adsorbents with Different Ligand Composition for Bilirubin Conjugated with Albumin" @default.
- W1996344434 cites W1983325168 @default.
- W1996344434 cites W2015566312 @default.
- W1996344434 cites W2017830542 @default.
- W1996344434 cites W2032420355 @default.
- W1996344434 cites W2043629625 @default.
- W1996344434 cites W2066123046 @default.
- W1996344434 cites W2092230574 @default.
- W1996344434 cites W2313258557 @default.
- W1996344434 doi "https://doi.org/10.1081/ss-200052186" @default.
- W1996344434 hasPublicationYear "2005" @default.
- W1996344434 type Work @default.
- W1996344434 sameAs 1996344434 @default.
- W1996344434 citedByCount "8" @default.
- W1996344434 countsByYear W19963444342012 @default.
- W1996344434 countsByYear W19963444342013 @default.
- W1996344434 countsByYear W19963444342016 @default.
- W1996344434 countsByYear W19963444342018 @default.
- W1996344434 countsByYear W19963444342019 @default.
- W1996344434 countsByYear W19963444342022 @default.
- W1996344434 crossrefType "journal-article" @default.
- W1996344434 hasAuthorship W1996344434A5003315472 @default.
- W1996344434 hasAuthorship W1996344434A5010942938 @default.
- W1996344434 hasAuthorship W1996344434A5016808440 @default.
- W1996344434 hasAuthorship W1996344434A5073529218 @default.
- W1996344434 hasConcept C112613896 @default.
- W1996344434 hasConcept C116569031 @default.
- W1996344434 hasConcept C126322002 @default.
- W1996344434 hasConcept C150394285 @default.
- W1996344434 hasConcept C165616093 @default.
- W1996344434 hasConcept C170493617 @default.
- W1996344434 hasConcept C178790620 @default.
- W1996344434 hasConcept C184651966 @default.
- W1996344434 hasConcept C185592680 @default.
- W1996344434 hasConcept C187428577 @default.
- W1996344434 hasConcept C2776125364 @default.
- W1996344434 hasConcept C2777513400 @default.
- W1996344434 hasConcept C2778597219 @default.
- W1996344434 hasConcept C43617362 @default.
- W1996344434 hasConcept C521977710 @default.
- W1996344434 hasConcept C55493867 @default.
- W1996344434 hasConcept C71924100 @default.
- W1996344434 hasConceptScore W1996344434C112613896 @default.
- W1996344434 hasConceptScore W1996344434C116569031 @default.
- W1996344434 hasConceptScore W1996344434C126322002 @default.
- W1996344434 hasConceptScore W1996344434C150394285 @default.
- W1996344434 hasConceptScore W1996344434C165616093 @default.
- W1996344434 hasConceptScore W1996344434C170493617 @default.
- W1996344434 hasConceptScore W1996344434C178790620 @default.
- W1996344434 hasConceptScore W1996344434C184651966 @default.
- W1996344434 hasConceptScore W1996344434C185592680 @default.
- W1996344434 hasConceptScore W1996344434C187428577 @default.
- W1996344434 hasConceptScore W1996344434C2776125364 @default.
- W1996344434 hasConceptScore W1996344434C2777513400 @default.
- W1996344434 hasConceptScore W1996344434C2778597219 @default.
- W1996344434 hasConceptScore W1996344434C43617362 @default.
- W1996344434 hasConceptScore W1996344434C521977710 @default.
- W1996344434 hasConceptScore W1996344434C55493867 @default.
- W1996344434 hasConceptScore W1996344434C71924100 @default.
- W1996344434 hasIssue "7" @default.
- W1996344434 hasLocation W19963444341 @default.
- W1996344434 hasOpenAccess W1996344434 @default.
- W1996344434 hasPrimaryLocation W19963444341 @default.
- W1996344434 hasRelatedWork W2023715417 @default.
- W1996344434 hasRelatedWork W2062528380 @default.
- W1996344434 hasRelatedWork W2073460438 @default.
- W1996344434 hasRelatedWork W2264230211 @default.
- W1996344434 hasRelatedWork W2283940825 @default.
- W1996344434 hasRelatedWork W2407632771 @default.
- W1996344434 hasRelatedWork W2408568198 @default.
- W1996344434 hasRelatedWork W2414398362 @default.
- W1996344434 hasRelatedWork W2415472473 @default.
- W1996344434 hasRelatedWork W2077597829 @default.
- W1996344434 hasVolume "40" @default.
- W1996344434 isParatext "false" @default.
- W1996344434 isRetracted "false" @default.
- W1996344434 magId "1996344434" @default.
- W1996344434 workType "article" @default.