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• W1996377811 abstract "Oncotype DX® is a multigene assay that provides prognostic information in terms of 10-year distant recurrence and predicts the likelihood of adjuvant chemotherapy benefit in estrogen receptor positive breast cancer patients, based on the expression of a panel of 21 genes (16 cancer-related and five reference genes) from a tumor specimen (core biopsy or surgical resection). It has been validated using multiple prospectively designed studies of archived tumor specimens from well-controlled clinical studies. In different countries with varying therapeutic approaches, using Oncotype DX has consistently resulted in a significant reduction in the number of patients who are prescribed chemotherapy, and in addition, it can identify a smaller subset of patients who would benefit from chemotherapy among patients who would otherwise receive endocrine therapy alone." @default.
• W1996377811 created "2016-06-24" @default.
• W1996377811 creator A5051306896 @default.
• W1996377811 date "2013-02-01" @default.
• W1996377811 modified "2023-10-18" @default.
• W1996377811 title "Overview of the use of Onco<i>type</i>DX^®as an additional treatment decision tool in early breast cancer" @default.
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• W1996377811 doi "https://doi.org/10.1586/era.12.174" @default.
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