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- W1996389615 endingPage "366" @default.
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- W1996389615 abstract "Mouse models of human genetic disorders provide a valuable resource for investigating the pathogenesis of genetic disease and for testing potential therapies. The high degree of resolution of linkage mapping in the mouse allows mutant phenotypes to be mapped precisely which, combined with the accurate definition of areas of homology between the mouse and human genomes, greatly facilitates the identification of mouse models. We describe here mouse models of human single gene disorders dividing them into three categories depending on the information available; phenotypic similarities, comparative mapping and identification of the underlying genetic lesion." @default.
- W1996389615 created "2016-06-24" @default.
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- W1996389615 date "1992-06-01" @default.
- W1996389615 modified "2023-10-13" @default.
- W1996389615 title "Mouse models of human single gene disorders I: Non-transgenic mice" @default.
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- W1996389615 doi "https://doi.org/10.1002/bies.950140602" @default.
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