Matches in SemOpenAlex for { <https://semopenalex.org/work/W1996443144> ?p ?o ?g. }
- W1996443144 endingPage "122" @default.
- W1996443144 startingPage "117" @default.
- W1996443144 abstract "In cerebral ischemic preconditioning (IPC), a first sublethal ischemia increases the resistance of neurons to a subsequent severe ischemia. Despite numerous studies, the mechanisms are not yet fully understood. Our goal is to develop an in vitro model of IPC on hippocampal organotypic slice cultures. Instead of anoxia, we chose to apply varying degrees of hypoxia that allows us various levels of insult graded from mild to severe. Cultures are exposed to combined oxygen and glucose deprivation (OGD) of varying intensities, ranging from mild to severe, assessing both the electrical activity and cell death. IPC was accomplished by exposure to the mildest ischemia condition (10% of O2 for 15 min) 24 h before the severe deprivation (5% of O2 for 30 min). Interestingly, IPC not only prevented delayed ischemic cell death 6 days after insult but also the transient loss of evoked potential response. The major interest and advantage of this system over both the acute slice preparation and primary cell cultures is the ability to simultaneously measure the delayed neuronal damage and neuronal function." @default.
- W1996443144 created "2016-06-24" @default.
- W1996443144 creator A5015627354 @default.
- W1996443144 creator A5019314842 @default.
- W1996443144 creator A5037451153 @default.
- W1996443144 creator A5052687230 @default.
- W1996443144 creator A5062379106 @default.
- W1996443144 creator A5084034589 @default.
- W1996443144 date "2005-07-01" @default.
- W1996443144 modified "2023-10-12" @default.
- W1996443144 title "Hypoxia/hypoglycemia preconditioning prevents the loss of functional electrical activity in organotypic slice cultures" @default.
- W1996443144 cites W193763600 @default.
- W1996443144 cites W1965724936 @default.
- W1996443144 cites W1971646621 @default.
- W1996443144 cites W1976495888 @default.
- W1996443144 cites W1996721095 @default.
- W1996443144 cites W2005796936 @default.
- W1996443144 cites W2009191140 @default.
- W1996443144 cites W2009812062 @default.
- W1996443144 cites W2010085531 @default.
- W1996443144 cites W2011270545 @default.
- W1996443144 cites W2020463662 @default.
- W1996443144 cites W2022316962 @default.
- W1996443144 cites W2025959962 @default.
- W1996443144 cites W2036553110 @default.
- W1996443144 cites W2038511780 @default.
- W1996443144 cites W2048922211 @default.
- W1996443144 cites W2052119252 @default.
- W1996443144 cites W2067763142 @default.
- W1996443144 cites W2067900166 @default.
- W1996443144 cites W2079054696 @default.
- W1996443144 cites W2120670195 @default.
- W1996443144 cites W2123351961 @default.
- W1996443144 cites W2138471282 @default.
- W1996443144 cites W2144918294 @default.
- W1996443144 cites W2156051089 @default.
- W1996443144 doi "https://doi.org/10.1016/j.brainres.2005.05.063" @default.
- W1996443144 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16005858" @default.
- W1996443144 hasPublicationYear "2005" @default.
- W1996443144 type Work @default.
- W1996443144 sameAs 1996443144 @default.
- W1996443144 citedByCount "26" @default.
- W1996443144 countsByYear W19964431442012 @default.
- W1996443144 countsByYear W19964431442013 @default.
- W1996443144 countsByYear W19964431442014 @default.
- W1996443144 countsByYear W19964431442015 @default.
- W1996443144 countsByYear W19964431442017 @default.
- W1996443144 countsByYear W19964431442018 @default.
- W1996443144 countsByYear W19964431442019 @default.
- W1996443144 countsByYear W19964431442021 @default.
- W1996443144 crossrefType "journal-article" @default.
- W1996443144 hasAuthorship W1996443144A5015627354 @default.
- W1996443144 hasAuthorship W1996443144A5019314842 @default.
- W1996443144 hasAuthorship W1996443144A5037451153 @default.
- W1996443144 hasAuthorship W1996443144A5052687230 @default.
- W1996443144 hasAuthorship W1996443144A5062379106 @default.
- W1996443144 hasAuthorship W1996443144A5084034589 @default.
- W1996443144 hasConcept C126322002 @default.
- W1996443144 hasConcept C134018914 @default.
- W1996443144 hasConcept C148762608 @default.
- W1996443144 hasConcept C169760540 @default.
- W1996443144 hasConcept C178790620 @default.
- W1996443144 hasConcept C185263204 @default.
- W1996443144 hasConcept C185592680 @default.
- W1996443144 hasConcept C190283241 @default.
- W1996443144 hasConcept C2779311647 @default.
- W1996443144 hasConcept C2780668416 @default.
- W1996443144 hasConcept C29694410 @default.
- W1996443144 hasConcept C31573885 @default.
- W1996443144 hasConcept C42219234 @default.
- W1996443144 hasConcept C540031477 @default.
- W1996443144 hasConcept C541997718 @default.
- W1996443144 hasConcept C55493867 @default.
- W1996443144 hasConcept C555293320 @default.
- W1996443144 hasConcept C71924100 @default.
- W1996443144 hasConcept C7836513 @default.
- W1996443144 hasConcept C86803240 @default.
- W1996443144 hasConceptScore W1996443144C126322002 @default.
- W1996443144 hasConceptScore W1996443144C134018914 @default.
- W1996443144 hasConceptScore W1996443144C148762608 @default.
- W1996443144 hasConceptScore W1996443144C169760540 @default.
- W1996443144 hasConceptScore W1996443144C178790620 @default.
- W1996443144 hasConceptScore W1996443144C185263204 @default.
- W1996443144 hasConceptScore W1996443144C185592680 @default.
- W1996443144 hasConceptScore W1996443144C190283241 @default.
- W1996443144 hasConceptScore W1996443144C2779311647 @default.
- W1996443144 hasConceptScore W1996443144C2780668416 @default.
- W1996443144 hasConceptScore W1996443144C29694410 @default.
- W1996443144 hasConceptScore W1996443144C31573885 @default.
- W1996443144 hasConceptScore W1996443144C42219234 @default.
- W1996443144 hasConceptScore W1996443144C540031477 @default.
- W1996443144 hasConceptScore W1996443144C541997718 @default.
- W1996443144 hasConceptScore W1996443144C55493867 @default.
- W1996443144 hasConceptScore W1996443144C555293320 @default.
- W1996443144 hasConceptScore W1996443144C71924100 @default.
- W1996443144 hasConceptScore W1996443144C7836513 @default.
- W1996443144 hasConceptScore W1996443144C86803240 @default.
- W1996443144 hasIssue "1-2" @default.